<Original Article>Expression of proteoglycan mRNA in human temporomandibular joint disks in temporomandibualr disorders
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概要
- 論文の詳細を見る
The purpose of this study was to investigate the expression of PG mRNA in human temporomandibular joint (TMJ) disks from patients with temporomandibular disorders (TMD). Total RNA was isolated from the TMJ disks. All patients had undergone diskectomy under general anethesia. RT-PCR was performed using primers for the proteoglycans, aggrecan and decorin. On electrophoresis of a lysate of human TMJ disks, decorin was recognized in each sample. In the calcified part of the disk which we recognized visually, aggrecan was also recognized. These results suggest that TMJ disks contain decorin, and are fibrous tissue. If the disk was subjected to excessive compression in addition to tension, cells similar to chondrocytes and expression of aggrecan was induced. Calcification would be initiated in the part of the disk experiencing the increased compression.
- 東京医科歯科大学の論文
著者
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Amagasa T
Tokyo Medical And Dental Univ. Tokyo Jpn
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Amagasa Teruo
Maxillofacial Surgery Graduate School Tokyo Medical And Dental University Tokyo Japan
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Amagasa Teruo
Maxillofacial Surgery Maxillofacial Reconstruction And Function Division Of Maxillofacial And Neck R
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Kino Koji
Temporomandibular Joint Clinic, Faculty of Dentistry; Tokyo Medical and Dental University
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Amagasa Teruo
Dept Of Maxillofacial Surgery Maxillofacial Reconstruction And Function Division Of Maxillofacial An
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Kino K
Temporomandibular Joint Clinic Tokyo Medical And Dental University
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Kino Koji
Temporomandibular Joint And Occlusion Comprehensive Oral Health Care Comprehensive Patient Care Grad
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Shibuya Tomoaki
Temporomandibular Joint And Occlusion Comprehensive Oral Health Care Comprehensive Patient Care Grad
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Shibuya Tomoaki
Dept of Maxillofacial Surgery, Maxillofacial Reconstruction and Function, Division of Maxillofacial
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Shibuya Tomoaki/Kino
Dept of Maxillofacial Surgery, Maxillofacial Reconstruction and Function, Division of Maxillofacial
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Shibuya Tomoaki/kino
Dept Of Maxillofacial Surgery Maxillofacial Reconstruction And Function Division Of Maxillofacial An
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