<SESSION>CAN OXIDATION OF TRITIUM GAS IN INTESTINE BE SUPPRESSED BY A DRUG IN RATS?
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概要
- 論文の詳細を見る
Clindamycin is known as an antibiotic efficatious against intestinal anaerobes. Administration of norfloxacin or clindamycin to rats began 1,2,3 of 4 days before commencement of exposure to tritium gas respectively and kept up until the day before exposure to tritium gas. After exposure to tritium gas (HT) for 2 hours, rats were sacrificed and tritium activity of various tissues and blood were determined. Tritium concentration in blood decreased in proportion to the period of administration of a drug. In the case of norfloxacin, tritium concentration in rat body decreased 1/5 that in non-treated rats. On the other hand, when administration of clindamycin began the day of exposure and kept up for 4 days, the biological half life of administrated rats was shortend to 3/5 that of non-treated rats.
- 核融合科学研究所の論文
著者
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一政 満子
茨城大学 理学部
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ICHIMASA MICHIKO
Department of Environmental Sciences, Faculty of Science, Ibaraki University
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ICHIMASA YUSUKE
Department of Environmental Sciences, Faculty of Science, Ibaraki University
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AKITA YASUKAZU
Department of Biology, Faculty of Science, Ibaraki University
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Ichimasa Yusuke
Department Of Biology Faculty Of Science Ibaraki University
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Ichimasa Michiko
日本原子力研究所
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Ichimasa Michiko
Department Of Biology Faculty Of Science Ibaraki University
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Shiba Hajime
Department Of Biology Faculty Of Science Ibaraki University
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Akita Y
Department Of Biology Faculty Of Science Ibaraki University
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Akita Yasukazu
Department Of Biology Faculty Of Science Ibaraki University
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Chikuuti Masaaki
Department of Biology, Faculty of Science, Ibaraki University
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Chikuuti Masaaki
Department Of Biology Faculty Of Science Ibaraki University
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Iwata Yoshiyuki
Res. Center For Charged Particle Therapy National Inst. Of Radiological Sciences
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