Is adjuvant chemotherapy by continuous infusion 5-fluorouracil plus daily low dose cisplatin useful in advanced (stageIV) pancreatic cancer ?

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概要

• 論文の詳細を見る

• Thirty-five patients were analyzed in this study to elucidate the usefulness of adjuvant chemotherapy by continuous infusion of 5-fluorouracil plus daily low-dose cisplatin after resection in advanced (stage IV) pancreatic cancer. The patients were divided into 3 groups : 8 patients were treated with the above therapy (group A), 16 patients with conventional chemotherapy (group B), and 11 patients received no chemotherapy whatsoever (group C). Mean survival time was longer in group A than in group B and C. These results were remarkable given that the patients had been diagnosed as stage IVb and curability C. Al-though the occurrence of adverse effects was higher in group A, none of them were severe. We conclude in this retrospective study that continuous infusion of 5-fluorouracil plus daily low-dose cisplatin is effective adjuvant chemotherapy in the treatment of advanced cancer of the pancreas. Therefore, the prospective trial will be necessary in near future.

• 札幌医科大学の論文

著者

• HIRATA KOICHI

  First Department of Surgery, Sapporo Medical University School of Medicine

• HATA FUMITAKE

  First Department of Surgery, Sapporo Medical University School of Medicine

• OIKAWA IKUO

  First Department of Surgery, Sapporo Medical University School of Medicine

• Hata Fumitake

  札幌医科大学 医学部外科学第一講座

• Hata F

  Department Of Surgery Sapporo Medical University School Of Medicine

• Hata Fumitake

  First Department Of Surgery Sapporo Medical University School Of Medicine

• Hata Fumitake

  Department Of Surgery Sapporo Medical University School Of Medicine

• Hata Fumitake

  札幌医科大学 解剖

• Hata Fumitake

  First Department Of Surgery Sapporo Medical University

• Oikawa Ikuo

  First Department Of Surgery Sapporo Medical University School Of Medicine

• Hata Fumitake

  Department Of Surgery (section 1). Sapporo Medical University School Of Medicine

• Hirata Koichi

  First Department Of Surgery Sapporo Medical University

• Oikawa I

  First Department Of Surgery Sapporo Medical University School Of Medicine

• Hirata Koichi

  First Department Of Surgery Cancer Research Institute Sapporo Medical University

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