<症例報告>急性腎不全,高CPK血症を伴い,急激にケトアシドーシスを呈した非自己免疫性劇症型1型糖尿病の1例

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We present a 40 year male patient who developed diabetic ketoacidosis with acute renal failure and high serum values of CPK and uric acid. Because of acute onset of ketoacidosis during several days with an elevation of serum amylase, negative findings of antibodies associated with autoimmune type 1 diabetes mellitus, he was diagnosed of a non-autoimmune, fuluminant, type 1 diabetes mellitus, which is a newly established subtype of type 1 diabetes mellitus. Since the patient's post-prandial plasma glucose was extremely high (1123 mg/dl) when he developed ketoacidosis, the severe dehydration due to extreme hyperglycemia might have caused acute renal failtire and rhabdomyolysis.
獨協医科大学の論文
2003-03-25