The Effect of Losartan and Amlodipine on Left Ventricular Diastolic Function and Atherosclerosis in Japanese Patients with Mild-to-Moderate Hypertension (J-ELAN) study

スポンサーリンク

概要

• 論文の詳細を見る
• 2011-03-01

著者

• Hori Masatsugu

  Department Of Cardiology Ehime Prefectural Imabari Hospital

• Yamazaki Tsutomu

  Department Of Applied Chemistry Graduate School Of Engineering Tokyo University Of Agriculture And T

• Ohtsu Hiroshi

  Department of Applied Quantum Medical Engineering, School of Engineering, Tohoku University

• Yamamoto Kazuhiro

  Department of Biochemistry, Kinki University

• HORIGUCHI Yasunori

  Horiguchi Clinic

• OZAKI Hitoshi

  Ozaki Clinic

• TAKAYASU Ken

  Takayasu Clinic

• AKEHI Noriyuki

  Settsuiseikai Hospital

• FUKUI Sugao

  Kawasaki Hospital

• SAKAI Akihiko

  Sakai Clinic

• KODAMA Mineo

  Kodama Clinic

• SHIMONAGATA Tsuyoshi

  Shimonagata Clinic

• KOBAYASHI Keiji

  Kobayashi Clinic

• OTA Mitsushige

  Ohta Clinic

• EBISUNO Shoji

  Ebisuno Clinic

• KATSUBE Yoshiki

  Katsube Clinic

• YAMAZAKI Tsutomu

  Department of Clinical Epidemiology & Systems, The University of Tokyo

関連論文

• Impact of Diabetes Mellitus on Rehospitalization for Heart Failure Among Survivors of Acute Myocardial Infarction in the Percutaneous Coronary Intervention Era
• OE-294 A Functional Variation in a Gene Encoding One of Galectin-2 Binding Proteins Confers Risk of Myocardial Infarction in Asian Populations(OE50,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Oral Presentation (English),The 73rd A
• OE-009 Identification of a Locus on Chromosome 5p that Confers Risk of Coronary Artery Disease by Genome Wide Association Study(OE02,ACS/AMI (Basic) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• FRS-071 Constitutive Autophagy Is Required to Maintain Cardiac Structure and Function in Aged Mouse Heart(FRS15,Novel Molecular Mechanisms of Heart Failure 1 (M),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circul
• FRS-061 Cardiac-specific Disruption of Calpain4 Revealed Its Cardioprotective Role in Response to Pressure Overload(FRS13,Novel Molecular Mechanisms of Heart Failure 2 (M),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japan
• FRS-004 Large Scale SNPs Association Study to Identify Genes Confer Risk of Myocardial Infarction(FRS1,New Molecules for Cardiovascular Regulation (M),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Socie
• 2 Total Management of Vulnerable Patients after Acute Myocardial Infarction(Comprehensive Risk Management for Prevention of Coronary Artery Disease,Symposium 16 (SY-16) (H),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• 4 Primary PCI versus CABG in Patients with Acute Myocardial Infarction due to the Occlusion of the Left Main Coronary Artery(Therapeutic Decision Making for Coronary Artery Disease Among PCI, CABG, and Medication,Symposium 3 (SY-03) (IHD),The 73rd Annual
• 2 Biomarkers, Single Nucleotide Polymorphisms and Cardiovascular Risk after Acute Myocardial Infarction : Observations from the Osaka Acute Coronary Insufficiency Study (OACIS)(Biomarkers, Genetic Polymorphism, and Risk Estimation,Symposium 1 (SY-01) (H),
• Up-Regulation of Cell Adhesion Molecule Genes in Human Endothelial Cells Stimulated by Lymphotoxin Alpha : DNA Microarray Analysis
• PJ-864 Signs of circulatory failure early hours after PCPS may predict prognosis in patients with CPAOA and PCPS(Emergency care / CPR(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-225 Lymphotoxin-alpha Regulates Monocyte Adhesion to Endothelial Cells by Up-regulation of Cell Adhesion Molecules via PI3K-Akt-NFkB Pathway in Human Endothelial Cells(Atherosclerosis, basic(06)(IHD),Poster Session(Japanese),The 72nd Annual Scientific
• PJ-054 Increased Cardiac Glucocorticoid Contribute to Promoting Cardiac Hypertrophy(Cardiac hypertrophy, basic/clinical(02)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PE-334 IKKβ/NF-κB Pathway Protects Hearts from Hemodynamic Stress Mediated through Regulating MnSOD Expression(Heart failure, basic(03)(M),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PE-066 Cardiovascular Events, Age and Time to Develop Metabolic Syndrome after the Initial Diagnosis of Central Obesity(Diabetes/Obesity/Metabolic syndrome(04)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Socie
• OJ-214 Clinical Features and Outcomes of Octogenarians with Acute Myocardial Infarction(Acute coronary syndrome, basic / clinical(02)(IHD),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-040 Combined Evaluation of N-terminal pro-BNP and cardiac Troponin T in the Convalescent Stage of Myocardial Infarction to Predict Future Events.(Acute myocardial infarction, clinical(diagnosis/treatment)(03)(IHD),Oral Presentation(Japanese),The 72nd A
• OJ-039 Effect of Admission Hyperglycemia and Intracoronary Thrombectomy on 30-day Mortality in Non-Diabetic Patients with Acute Myocardial Infarction.(Acute myocardial infarction, clinical(diagnosis/treatment)(03)(IHD),Oral Presentation(Japanese),The 72nd
• OE-255 Cross-talk between p38 Dependent Pathological Remodeling Cascade and Cardiac Adaptive Responses(Cardiac hypertrophy, basic/clinical(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PE-152 Adiponectin Deficiency Suppresses ABCA1 Expression and ApoA-I Synthesis in the Liver(Atherosclerosis, basic(04)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• A functional SNP in ITIH3 is associated with susceptibility to myocardial infarction
• Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction
• DPE-025 Serum Oxysterol Levels are Elevated in a Patient with Giant Necrotic Tendon Xanthomatosis and Carotid and Coronary Atherosclerosis(DPE05,Lipid Disorders (H),Digital Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circul
• PE-151 Adiponectin Promotes Cholesterol Efflux from Human Macrophages throuth ABCA1-dependent Pathway(Atherosclerosis, basic(04)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• FRS-095 Impact of Hyperuricemia and Renal Dysfunction on Cardiovascular Events after the Onset of Acute Myocardial Infarction(Renal Dysfunction and Cardiovascular Disease(H),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circ
• Effect of Early Use of Low-Dose Pravastatin on Major Adverse Cardiac Events in Patients With Acute Myocardial Infarction : The OACIS-LIPID Study
• 1 Impact of Renal Dysfunction on Prognosis after the Onset of Acute Myocardial Infarction(Cardiorenal Syndrome and Hypertensive Heart Diseases, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Identification of Uncomplicated Patients With Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention : Are These Patients Suitable for Early Discharge?
• PJ-152 A functional SNP in the Proteasome Subunit Alpha Type 6 Gene confers Risk of Myocardial Infarction in Japanese Population(Acute myocardial infarction, basic-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-212 Identification of a Novel non-coding RNA, MIAT, that Confers Risk of Myocardial Infarction(Genetics/Genetically engineered models/Gene therapy-2(H/M), The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-340 Large-Scale Genetic Association Study of 30 Inflammation-Related Genes for Myocardial Infarction Using Tag SNPs from HapMap Data(Genetics/Genetically engineered models/Gene therapy-1 (M) OJ57,Oral Presentation (Japanese),The 70th Anniversary Annual
• Genome-wide association study to identify genes related to myocardial infarction
• A high-throughput SNP typing system for genome-wide association studies in patients with myocardial infarction
• Inhibition of Cardiac Remodeling by Pravastatin Is Associated with Amelioration of Endoplasmic Reticulum Stress
• Serum Osteoprotegerin as a Screening Tool for Coronary Artery Calcification Score in Diabetic Pre-Dialysis Patients
• PJ-084 Diastolic function is impaired at the noninfarcted region in patients with LV remodeling after myocardial infarction(Echo/Doppler(11)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Long-Term Oral Administration of Dipyridamole Improves Both Cardiac and Physical Status in Patients with Mild to Moderate Chronic Heart Failure : A Prospective Open-Randomized Study
• 3 Single Nucleotide Polymorphisms Associated with Drug Effectiveness on Long-term Mortality after Acute Myocardial Infarction(Plenary Session 7 (PL-7) (M) Genomic Approaches to Cardiovascular Diseases : Present and Future,Special Program,The 72nd Annual S
• PJ-162 An Elevated Cardiac Troponin T Level in Patients with OMI is Indicative of Adverse Clinical Outcomes(Acute myocardial infarction, clinical (diagnosis/treatment)-7, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• FRS-063 Preceding Glycometabolism, Mechanical Complications and 30-day Mortality in Patients with Acute Myocardial Infarction and no History of Diagnosed Diabetes Mellitus(Diabetes/Obesity (clinical), The 71st Annual Scientific Meeting of the Japanese Cir
• 4 Minimally Elevated Troponin T at Chronic Phase can Identify Vulnerable Patients with Myocardial Infarction(New Evidence of Coronary Artery Disease-Pathogenesis, Diagnosis and Therapy, The 71st Annual Scientific Meeting of the Japanese Circulation Societ
• 3 Clinical Impact of Intracoronary Thrombectomy and Distal Protection Device on 30-day Mortality in Patients with Acute Myocardial Infarction(New Horizon in Coronary Interventions for Acute Coronary Syndrome, The 71st Annual Scientific Meeting of the Japa
• PJ-583 Influence of Withdrawal of Statin on Outcome in Patients with Acute Myocardial Infarction(Acute myocardial infarction, clinical (diagnosis/treatment)-10 (IHD) PJ98,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japa
• PE-007 Effect of A252G Polymorphism at Lymphotoxin Alpha Gene on Mortality after Myocardial Infarction is Modified by Statin Treatment(Acute myocardial infarction, clinical (diagnosis/treatment)-5 (IHD) PE2,Poster Session (English),The 70th Anniversary An
• OJ-132 Impact of Atrial Flutter and Fibrillation on Development of Stroke after Acute Myocardial Infarction(Acute coronary syndrome, basic/clinical-2 (IHD) OJ22,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Ci
• FRS-008 Clinical Impact of Smoking Cessation on Cardiac Events in Survived Patients with Acute Myocardial Infarction(Strategies to Acute Myocardial Infarction-2 (IHD) FRS2,Featured Research Session,The 70th Anniversary Annual Scientific Meeting of the Jap
• FRS-007 Clinical Impact of Metabolic Syndrome on Cardiac Events in Survived Patients with Acute Myocardial Infarction(Strategies to Acute Myocardial Infarction-2 (IHD) FRS2,Featured Research Session,The 70th Anniversary Annual Scientific Meeting of the Ja
• Impact of 87 Gene Polymorphisms on Mortality and Recurrent Events After Myocardial Infarction(Acute Myocardial Infarction, Clinical (Pathophysiology) 6 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PE-159 Familial Intrahepatic Cholestasis 1 (FIC1) Gene Product, a Novel Contributor for Cholesterol Efflux(Atherosclerosis, basic-4 (H) PE27,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-047 The Combined Therapy of Angiotensin Converting Enzyme Inhibitor, Angiotensin II Receptor Blocker and Beta-blockers Submaximally Limits Infarct Size(Acute Myocardial Infarction, Basic 2 (IHD) : PJ8)(Poster Session (Japanese))
• PJ-046 Celiprolol, a Selective β_1-Adrenoceptor Antagonist, Limits Infarct Size via NO-dependent Mechanisms(Acute Myocardial Infarction, Basic 2 (IHD) : PJ8)(Poster Session (Japanese))
• Changes in gene expression profile by HCV core protein in cultured liver cells : analysis by DNA array assay
• Presenilin 2 Regurates Excitation-contraction Coupling in Hearts(Excitation-contraction Coupling/Ion Channel 1 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-524 The Protective Role of STAT6 in Response to Pressure Overload in Vivo(Molecular Biology, Myocardium 2 (M) : OJ64)(Oral Presentation (Japanese))
• OJ-023 Cardiac-specific Over-expression of Sarcolipin Inhibits the Sarcoplasmic Reticulum Ca^ ATPase (SERCA2a) and Reduces the Cardiac Function in Mice(Excitation-Contraction Coupling/Ion Channel (A) : OJ3)(Oral Presentation (Japanese))
• OJ-020 Presenilin 2 Directly Interacts with Cardiac Ryanodine Receptor(Excitation-Contraction Coupling/Ion Channel (A) : OJ3)(Oral Presentation (Japanese))
• OE-367 The Ca^/calmodulin-dependent Protein Kinase II Induces Cardiac Myocyte Hypertrophy through the Activation of Apoptosis Signal-regulating Kinase 1 and Nuclear Factor-κB(Cardiac Hypertrophy, Basic and Clinical 1 (M) : OE46)(Oral Presentation (Eng
• Cardiac-Specific Overexpression of a High Ca^ Affinity Mutant of Cardiac Ca^ ATPase Attenuates in Vivo Pressure Overload Cardiac Hypertrophy
• The Small G Protein Rac1 Induce Cardiac Myocyte Hypertrophy through the Activation of Apoptosis Signal-Regulating Kinase1 and Nuclear Factor-Kappa B
• Cardiac-Specific Disruption of Raf-1 Gene Induces Apoptosis and Cardiac Dysfunction
• Amino acids ^KDDKPV^ in the cytosolic domain of SERCA2a are critical for functional association with PLN in vivo
• Abnormal Myocardial Free Fatty Acid Utilization Deteriorates With Morphological Changes in the Hypertensive Heart
• Mouse uroguanylin is localized in the kidney outer medulla and regulated by dehydration
• The ATP-sensitive Potassium Channel Opener, Nicorandil, Reduces No-reflow Phenomenon and Infarct Size in the Canine Heart
• Adenosine-Induced Cardiac Gene Expression of Ischemic Murine Hearts Revealed by cDNA Array Hybridization
• Polymyxin B-immobilized fiber may improve hemodynamics in patients with severe sepsis and septic shock via the attenuation of nitric oxide
• PE-433 Reduction in Hemoglobin-Oxygen Affinity Results in the Improvement of Exercise Capacity in Mice with Chronic Heart Failure(Heart failure, basic-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OE-046 ASK1-p38 MAP Kinase Pathway Plays an Important Role in Physiological Hypertrophy Induced by Exercise Training(Cardiac hypertrophy, basic/clinical-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• FRS-066 Autophagy in Cardiomyocyte is Essential for Maintenance of Cardiac Function(Heart Failure, Cardiac Remodeling and Cardiomyopathy 1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OE-068 Cardiac-specific Activation of Apoptosis Signal-regulating Kinase 1 Leads to Cardiac Dysfunction through both Apoptotic and Non-apoptotic Cell Death(Cell death, apoptosis/necrosis (M) OE12,Oral Presentation (English),The 70th Anniversary Annual Sci
• OE-067 Non-apoptotic Cell Death in Cardiac Injury : The Role of Cyclophilin D(Cell death, apoptosis/necrosis (M) OE12,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• 4 The Role of Mitogen-activated Protein Kinase Family in the transition to Heart Failure(AHA/JCS Joint Symposium (AHA) (M) : Molecular Mechanism of Heart Failure)(Special Program)
• PJ-227 Diastolic Wall Strain can Noninvasively Predict Hemodynamic Deterioration Unassociated with Systolic Dysfunction in Hypertensive Hearts(PJ038,Echo/Doppler (New Technology) 1 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Ja
• OE-376 Diastolic Wall Strain Reflects the Myocardial Fibrosis in Heart Transplanted Patients(OE64,Heart Failure (Diagnosis) (M),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• 1 Evaluation of Diastolic Function Using Left Ventricular Endocardial and Epicardial Movement(Frontiers in Diagnostic Echocardiography,Symposium 14 (SY-14) (M),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-629 Bisoprolol Dose-dependently Improves the Prognosis of Diastolic Heart Failure through Its Scavenging Ability and the Inhibition of Down-regulation of PGC-1α(Cardiac function, basic/clinical(04)(M),Poster Session(Japanese),The 72nd Annual Scientific
• PE-322 Analysis of RF signals with chaos theory may provide a novel marker of progressive LV fibrosis.(Echo/Doppler(07)(I),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-316 Blockade of Angiotensin II Type 1 Receptor Improves Hypertensive Diastolic Heart Failure at an Advanced Stage(Cardiac hypertrophy, basic/clinical-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-074 Diastolic Color Kinesis Can Noninvasively Detect Pharmacological Effects on LV Diastolic Function(Echo / Doppler-04, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-072 Usefulness of Diastolic Color Kinetic Imaging in the Assessment of LV Relaxation Regardless of LV Filling Pressure(Echo / Doppler-04, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Difference of Clinical Characteristics between Hypertensive Patients with and without Diastolic Heart Failure : The Roles of Diastolic Dysfunction and Renal Insufficiency
• Japanese multicenter clinical evaluation of the HeartMate vented electric left ventricular assist system
• Angiotensin Converting Enzyme Inhibitor Reduces Cardiac Hypertrophy and Fibrosis in Cardiomyopathic Hamsters via NO-dependent Mechanisms(Heart Failure, Basic 3 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-092 Activation of Adenosine A1 Receptors Inhibits Aldosterone Synthesis in Adrenal Glands(Metabolism/Biochemistry/Energetics-3 (M) PJ16,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Left ventricular mass index measured by quantitative gated myocardial SPECT with ^Tc-tetrofosmin : a comparison with echocardiography
• Estimation of the area at risk in myocardial infarction of rats by means of I-123 β-methyliodophenyl pentadecanoic acid imaging
• Characteristics of myocardial ^F-fluorodeoxyglucose positron emission computed tomography in dilated cardiomyopathy and ischemic cardiomyopathy
• OE-060 Apo B-48 Is a Good Marker for Coronary Risk and Impaired Metabolism of Chylomicron Remnants in Subjects with Metabolic Syndrome(Lipid disorders-1 (H) OE10,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Ci
• CHANGE OF α-ACTININ IN REPERFUSED MYOCARDIUM
• PE-284 Angiotensin Converting Enzyme Inhibitor And Angiotensin II Type1 Receptor Antagonist Differently Modulate Extracellular Matrix Regulatory System in Diastolic Heart Failure(Heart Failure, Clinical 10 (M) : PE49)(Poster Session (English))
• PE-182 Angiotensin II type1 Receptor Blocker Suppresses ROS Generation and Inflammatory Changes and Prevents Overt Diastolic Heart Failure in Hypertensive Hearts(Infection/Inflammation/Immunity 2 (H) : PE31)(Poster Session (English))
• Asymmetrical Dimethyl Arginine (ADMA) is a Novel Marker of Coronary Stent Restenosis
• OJ-442 Gq-stimulation along with low activity of proteasome induces cardiac apoptosis : Potential mechanism of transition from hypertrophy to failure(Heart Failure, Basic 3 (M) : OJ54)(Oral Presentation (Japanese))
• OJ-324 Antagonism of Aldosterone Receptor Attenuates Severity of Cardiac Dysfunction and Inflammation Induced by Chronic Blockade of NO Synthesis in Rats(Cardiovascular Pharmacology, Basic/Clinical 2 (H) : OJ39)(Oral Presentation (Japanese))
• Canine DNA Array as a Potential Tool for Combining Physiology and Molecular Biology : An Application for the Gene Expression Profile of Regional Ischemic Myocardium
• An Adenosine Analogue, Chloroadenosine, Attenautes Pressure-Overload Myocardial Hypertrophy in Mice
• The New Metalloproteinase Inhibitor Blocks Cardiac Hypertrophy Induced by both Phenylephrine and Angiotensin II
• OJ-522 Gene expression analyses of embryonic carcinoma cell P19.CL6 during the cardiomyocyte differentiation(Molecular Biology, Myocardium 2 (M) : OJ64)(Oral Presentation (Japanese))
• Relationship between Myocardial Flow Reserve by Oxygen-15 Water Positron Emission Tomography in the Subacute Phase of Myocardial Infarction and Left Ventricular Remodeling in the Chronic Phase
• PJ-195 Activation of Endoplasmic Reticulum-initiated Apoptotic Signaling Mediated by CHOP/GADD153 Contributes to Development of Cardiac Dysfunction in Pressure-overloaded Hearts(Heart failure, basic-6 (M) PJ33,Poster Session (Japanese),The 70th Anniversar

もっと見る 閉じる

スポンサーリンク