New Rapid Screening Method for Anti-Aging Compounds Using Budding Yeast and Identification of Beauveriolide I as a Potent Active Compound

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概要

• 論文の詳細を見る

• The chronological lifespan (CLS) of budding yeast is a model for the aging of post-mitotic cells in higher eukaryotes. We report here the development of a new method to assess yeast CLS. The new assay is simple, convenient and labor-saving. We applied this new method to screen natural compounds isolated from mushrooms and discovered beauveriolide I as a potent anti-aging agent.

• 2012-06-23

著者

• Ushimaru Takashi

  Faculty Of Science Shizuoka Univ.

• Kawagishi Hirokazu

  Faculty Of Agriculture Shizuoka University

• Ushimaru Takashi

  Faculty Of Science Shizuoka University

• Nakaya Shigeru

  Faculty Of Science Shizuoka University

• MIZUNO Saki

  Faculty of Science, Shizuoka University

• ISHIGAMI Hiroki

  Faculty of Science, Shizuoka University

• YAMAKAWA Yasuhiro

  Faculty of Agriculture, Shizuoka University

• Mizuno Saki

  Faculty Of Science Shizuoka University

• Yamakawa Yasuhiro

  Faculty Of Agriculture Shizuoka University

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• Characterization of Methylhydroquinone-Metabolizing Oxygenase Genes Encoded on Plasmid in Burkholderia sp. NF100(ENVIRONMENTAL BIOTECHNOLOGY)
• New Rapid Screening Method for Anti-Aging Compounds Using Budding Yeast and Identification of Beauveriolide I as a Potent Active Compound

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