Synthesis of Non-Steroidal Estrogen Receptor Antagonists R1128 A, B, C, and D via an Oxazoline-Promoted Iterative ortho-Lithiation Strategy
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概要
- 論文の詳細を見る
A concise total synthesis of non-steroidal estrogen receptor antagonists R1128 A–D (1a–1d) has been achieved using iterative ortho-lithiation of 2-(4-methoxyphenyl)-4,4-dimethyloxazoline (3) as the key reaction.
- The Chemical Society of Japanの論文
- 2012-01-15
著者
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Iwao Masatomo
Division Of Chemistry And Materials Science Graduate School Of Engineering Nagasaki University
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FUKUDA Tsutomu
Division of Chemistry and Materials Science, Graduate School of Engineering, Nagasaki University
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FUKUSHIMA Koichiro
Division of Chemistry and Materials Science, Graduate School of Engineering, Nagasaki University
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SANAI Susumu
Division of Chemistry and Materials Science, Graduate School of Engineering, Nagasaki University
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Sanai Susumu
Division Of Chemistry And Materials Science Graduate School Of Engineering Nagasaki University
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Fukushima Koichiro
Division Of Chemistry And Materials Science Graduate School Of Engineering Nagasaki University
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Fukuda Tsutomu
Division Of Chemistry And Materials Science Graduate School Of Engineering Nagasaki University
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- Synthesis of Non-Steroidal Estrogen Receptor Antagonists R1128 A, B, C, and D via an Oxazoline-Promoted Iterative ortho-Lithiation Strategy