Cytotoxic effects of polybasic acids, poly(alkenoic acid)s, and the monomers with various functional groups on human pulp fibroblasts
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概要
- 論文の詳細を見る
This study evaluated the cytotoxicity of various polybasic acids, poly(alkenoic acid)s, and the monomers with various acidic functional groups such as carboxyl, phosphoryl, and sulfo group. The cell growth of fibroblasts cultivated in medium containing polybasic acids and polymers up to the concentration to 5 mmol/L was not significantly different compared with that of control without their acids. On the other hand, the cell growth fibroblasts cultivated in medium containing 1 mmol/L of the monomers with acryloyloxy and phosphoryl or carboxyl group decreased remarkably compared with that of the control and the cells were probably lifeless. Those exposed to the monomers with a ether bond and a carboxyl group or a amide bond and a sulfo group was not significantly different compared with that of control.
- 日本歯科理工学会の論文
- 2011-11-01
著者
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KURATA Shigeaki
Department of Biomaterials and Devices, Kanagawa Dental College
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Kurata Shigeaki
Department Of Biomaterials And Devices Kanagawa Dental College
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Kawase Toshio
Department Of Natural Science Division Of Dental Bioengineering Kanagawa Dental College
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Kawase Toshio
Department Of Biochemistry Faculty Of Dentistry Tokyo Medical And Dental University
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Umemoto Kozo
Department Of Biomaterials And Devices Kanagawa Dental College
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Morishita Kumiko
Department Of Biomaterials And Devices Kanagawa Dental College
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