Adalimumab-associated Pulmonary Cryptococcosis
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概要
- 論文の詳細を見る
This is the first report of adalimumab-associated pulmonary cryptococcosis. A 56-year-old female with rheumatoid arthritis without a history of pulmonary disease was simultaneously administered adalimumab (40 mg/2 wks), methotrexate (4 mg/wk), and isoniazid (200 mg/day). Five months later, chest radiography revealed a small spiculated pulmonary nodule, and the laboratory test results, including levels of tumor markers and plasma β-D-glucan, were within normal ranges. Since the lesion continued to grow, even after discontinuing adalimumab, it was surgically resected. Grocott staining of the tissue sample revealed black-brown fungi, identified as Cryptococcus neoformans in culture. The patient now remains well, without adalimumab therapy.
- 2011-08-01
著者
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Kimura Hayato
Department Of Pathology Graduate School Of Medicine Osaka University
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Nagano Teruaki
Department Of Pathology Osaka Prefectural Hospital Organization Osaka Prefectural Medical Center For
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Nakatsuka Shin-ichi
Department Of Clinical Laboratory National Hospital Organization Osaka Minami Medical Center
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Sakaki Masayuki
Department Of Cardiovascular Surgery Kansai Rousai Hospital
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Iwata Takashi
Department Of Thoracic And Cardiovascular Surgery Kansai Rosai Hospital
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Iwata Takashi
Department Of Horticulture
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Nakatsuka Shin-ichi
Departments Of Pathology Kansai Rosai Hospital
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Suehiro Yasuo
Department Of Thoracic And Cardiovascular Surgery Kansai Rosai Hospital
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TOMITA Masuhiro
Departments of Orthopedic Surgery, Kansai Rosai Hospital
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Sakaki Masayuki
Department Of Thoracic And Cardiovascular Surgery Kansai Rosai Hospital
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Nagano Teruaki
Departments Of Pathology Kansai Rosai Hospital
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Tomita Masuhiro
Departments Of Orthopedic Surgery Kansai Rosai Hospital
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Sakaki Masayuki
Department Of Cardiovascular Surgery Kansai Rosai Hospital
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Suehiro Yasuo
Department Of Cardiovascular Surgery Kansai Rosai Hospital
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Kimura Hayato
Departments Of Pathology Kansai Rosai Hospital
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