Effects of Feeding Bifidobacterium longum and Inulin on Some Gastrointestinal Indices in Human Volunteers

スポンサーリンク

概要

• 論文の詳細を見る

• Interest in consumption of probiotic and prebiotics (indigestible oligosaccharides) to improve human gastrointestinal health is increasing. Consumption of beneficial probiotic bacteria combined with oligosaccharides may provide enhanced gastrointestinal benefits and improvements in internal health. The objective of this study was to evaluate the efectiveness of administering Bifidobacterium longum 1941 or B. longum BB536 and inulin to healthy, adult volunteers over 2-wk to observe changes in gastrointestinal indices (bacterial counts in stool, stool defecation frequency and consistency, and in organic acids, β-glucuronidase and β-glucosidase enzyme concentration, pH and moisture). A randomised, double-blind and placebo-controlled parallel group coparison was carried out. Subjects were randomly assigned to receive 25 mg of freeze-dried bacterial preparation containing≥1×1010 cfu/g of either B. longum 1941 and 475 mg inulin (n=10), B. longum BB536 and 475 mg inulin (n=10) or a placebo containing 475 mg inulin (n=10). Efficacy was based on comparison of initial values of gastrointestinal indices with final values. No significant difference between the baseline and the final reading among the three treatment groups was observed on bacterial counts, defecation frequency, stool consistency, pH, enzyme and organic acid concentrations or moisture percentage of stools. However, levels of butyric acid increased after subjects consumed probiotic capsules. No subjects reported worsening in gastrointestinal health after consumption of probiotic capsules. These results indicate that the administration of B. longum 1941 and B. longum BB536 did not significantly alter the intestinal environment, defecation frequency and faecal characteristics of healthy, human subjects. These results were possibly due to the short duration of the study and the participation of healthy, adult populations consuming probiotic bacteria and prebiotics.

• 日本ビフィズス菌センターの論文
• 2004-01-01

著者

• SHAH Nagendra

  School of Molecular Sciences, Victoria University

• Shah Nagendra

  School Of Life Sciences And Technology Victoria University Of Technology

• Shah Nagendra

  School Of Molecular Sciences Victoria University

• Bruno Frank

  School Of Molecular Sciences Victoria University

関連論文

• Acid and Bile Tolerance and The Cholesterol Removal Ability of Bifidobacteria Strains
• Characteristics of Bacteriocin Like Inhibitory Substances Produced by Lactobacillus acidophilus (BDLA-1, 2409 and MOLA-2), Lactobacillus fermentum (5174) and Lactobacillus plantarum (2903)
• Metabolism of Raffinose and Stachyose in Reconstituted Skim Milk and of n-Hexanal and Pentanal in Soymilk by Bifidobacteria
• Antimicrobial Substances Including Bacteriocins Produced by Lactic Acid Bacteria
• Bacteriocin Produced by Streptococcus thermophilus against Bifidobacterium Species
• Aflatoxin B_1 Binding Abilities of Probiotic Bacteria
• Effects of Feeding Bifidobacterium longum and Inulin on Some Gastrointestinal Indices in Human Volunteers
• Some Beneficial Effects of Probiotic Bacteria
• Adherence of Probiotic Bacteria to Human Colonic Cells
• Populations of Lactobacillus acidophilus, Bifidobacterium spp., and Lactobacillus casei in Commercial Fermented Milk Products

スポンサーリンク