頸部郭清術後に選択的動注化学放射線療法を施行した進行喉頭癌症例

概要

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The effectiveness of intra-arterial chemoradiotherapy (IACRT) against advanced laryngeal cancer has recently been reported. Yet, the indication of IACRT in cases with neck lymph node metastasis has not been discussed. Although planned neck dissection after radiotherapy is performed at many institutions, the radiotherapy often cause unfavorable postoperative complications. We treated a 57-year-old male, whose chief complaint was hoarseness, at our university hospital. Fiberoptic examination revealed an irregular tumor on the right subglottic lesion extending to the right ventricle. Images from computed tomography suggested the presence of metastatic cervical lymph nodes. Subglottic squamous cell carcinoma of the larynx (T2N2bM0) was histologically diagnosed. As a treatment, selective neck dissection for the cervical metastasis was first performed. During surgery, the supra-and inferior-thyroidal arteries were preserved. Ten days after the surgery, IACRT for the local tumor was given every other week using the supra-thyroidal artery. The IACRT was continued for five weeks and, as a result, the tumor has completely disappeared. The patient has been free from recurrence for more than a year.
日本喉頭科学会の論文
2010-12-01