妊娠期、泌乳期および新生子期におけるヤギの血漿中成長ホルモン(GH)、プロラクチン(PRL)およびインスリン様成長因子-I(IGF-I)の動態

概要

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The objectives of this research were to characterize plasma profiles of growth hormone (GH), prolactin (PRL) and insulin-like growth factor-I (IGF-I) during gestation and the lactation period in goats, as well as in their suckling growing kids. There were no obvious changes in the GH or PRL profiles during gestation, but secretion of both GH and PRL increased acutely after parturition. The elevated GH concentrations were maintained until 3 months after parturition, whereas the PRL concentrations decreased gradually after parturition. The elevated hormone concentrations are thought to be caused mainly by an increase in the secretory pulse amplitudes. In contrast to the GH and PRL profiles, the plasma IGF-I concentrations during late gestation were significantly higher than the post-parturition concentrations, and the IGF-I concentrations in late gestation decreased gradually until the day of parturition. The plasma GH, PRL and IGF-I concentrations in kids 1 week after birth were high, and concentrations of each hormone decreased thereafter. These results show that the increased secretory potencies of pituitary GH and PRL after parturition are caused mainly by an increase in the secretory pulse amplitudes and that plasma GH is inversely related to plasma IGF-I compared over gestation and the lactation period in goats.
日本繁殖生物学会の論文
1999-08-01