Distal Protection During Primary Coronary Intervention Can Preserve the Index of Microcirculatory Resistance in Patients With Acute Anterior ST-Segment Elevation Myocardial Infarction
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概要
- 論文の詳細を見る
Background: The objective of this study was to investigate whether a distal protection (DP) device can preserve the index of microcirculatory resistance (IMR) after primary percutaneous coronary intervention (PCI) in patients with anterior ST-segment elevation myocardial infarction (STEMI). Methods and Results: The study group of 36 consecutive patients with anterior STEMI were randomized into 2 groups of primary PCI with or without DP: stenting without DP (non-DP group, n=17) and with DP (DP group, n=19). The DP in all cases was Filtrap (Nipro, Japan). Following final coronary angiography after successful PCI, IMR was measured using PressureWireTM Certus (St Jude Medical, USA) at maximal hyperemia. The averaged IMR of the 36 patients with STEMI after primary PCI was 31.6U. The IMR in the DP group was significantly lower than that in the non-DP group (26.6±25.8U vs. 37.2±23.2U, P=0.03242). Conclusions: DP as an adjunctive therapy of PCI for acute anterior STEMI may have beneficial effects on myocardial microcirculation because of preservation of IMR. (Circ J 2011; 75: 94-98)
- 2010-12-25
著者
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Nanto Shinsuke
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine
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Yamashita Shizuya
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine
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Masuda Daisaku
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine
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Yamashita Shizuya
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine
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Masuda Daisaku
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine
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HAYASHI Yasuyuki
Senri Critical Care Medical Center, Osaka Saiseikai Senri Hospital
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Hayashi Toru
Division of Cardiovascular Medicine, Osaka National Hospital
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Nanto Shinsuke
Department Of Advanced Cardiovascular Therapeutics
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Okada Kenichiro
Critical & Cardiovascular Care Unit
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Kai Tatsuro
Senri Critical Care Medical Center Osaka Saiseikai Senri Hospital
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Doi Yasuji
Division Of Cardiology Kashiwara General Hospital
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Doi Yasuji
The First Department Of Medicine Osaka University School Of Medicine
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Doi Yasuji
Critical & Cardiovascular Care Unit
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Hayashi Toru
Critical & Cardiovascular Care Unit
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Ito Noritoshi
Critical & Cardiovascular Care Unit
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Sawano Hirotaka
Senri Critical Care Medical Center, Saiseikai Senri Hospital
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Sawano Hirotaka
Critical & Cardiovascular Care Unit
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Sawano Hirotaka
Senri Critical Care Medical Center Saiseikai Senri Hospital
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Hayashi Toru
Division Of Cardiovascular Medicine Osaka National Hospital
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Hayashi Yasuyuki
Senri Critical Care Medical Center Osaka Saiseikai Senri Hospital
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ITO Noritoshi
Senri Critical Care Medical Center, Critical & Cardiovascular Care Unit, Osaka Saiseikai Senri Hospi
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KUROZUMI Yuma
Senri Critical Care Medical Center, Critical & Cardiovascular Care Unit, Osaka Saiseikai Senri Hospi
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TONOMURA Daisuke
Senri Critical Care Medical Center, Critical & Cardiovascular Care Unit, Osaka Saiseikai Senri Hospi
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NATSUKAWA Tomoaki
Senri Critical Care Medical Center, Critical & Cardiovascular Care Unit, Osaka Saiseikai Senri Hospi
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OKADA Ken-ichiro
Division of Cardiovascular Medicine, Critical & Cardiovascular Care Unit, Osaka Saiseikai Senri Hosp
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Kurozumi Yuma
Senri Critical Care Medical Center Critical & Cardiovascular Care Unit Osaka Saiseikai Senri Hos
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Tonomura Daisuke
Senri Critical Care Medical Center Critical & Cardiovascular Care Unit Osaka Saiseikai Senri Hos
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Natsukawa Tomoaki
Senri Critical Care Medical Center Critical & Cardiovascular Care Unit Osaka Saiseikai Senri Hos
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Yamashita Shizuya
Department Of Cardiovascular Medicine Juntendo University School Of Medicine
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