Effect of Additives on Polymorphic Transition of Theophylline in Mechano-Chemical Processing
スポンサーリンク
概要
- 論文の詳細を見る
Mechano-chemical processing for the solid-state polymorphic transition of theophylline from Form I to Form II has been investigated. Contrarily to the same transition without mechanical energy, the transition was found to proceed without humidity and completed in about 24 h. The effect of additives on the transition was examined by co-grinding with purine derivatives. Except for uric acid, they delayed the transition to Form II, and the presence of paraxanthine resulted in going through a Form III of theophylline. In conclusion, additive selection has an important role for controlling the polymorphic transition and the appearance of polymorphs by mechano-chemical processing.
- 2010-07-01
著者
-
Kishi Yoshifumi
Department Of Chemical Engineering Tokyo University Of Agriculture And Technology
-
Matsuoka Masakuni
Department Of Chemical Engineering Tokyo University Of Agriculture And Technology
-
MATSUOKA Masakuni
Department of Chemical Engineering , Tokyo University of Agriculture and Technology
関連論文
- Solid-State Crystallization Behavior of Tetrabenzoporphyrin Organic Semiconductors
- Simplified heating time calculation using the Schmidt graphical method for PCB-contaminated capacitors undergoing the vacuum thermal recycling process
- Solid-State Crystallization of CuTBP (Copper Tetrabenzoporphyrin) Organic Semiconductor
- Analysis and Simulation of Phase Transformation Kinetics of Zeolite A from Amorphous Phases
- Nucleation Rates of Zeolite A Crystals from Clear Aluminosilicate Solutions
- BEHAVIOR OF PHASE TRANSITION AND HEAT TRANSFER CHARACTERISTICS IN A LATENT HEAT STORAGE UNIT WITH COMPOSITE MATERIAL
- Effect of Additives on Polymorphic Transition of Theophylline in Mechano-Chemical Processing
- Effects of Suspension Density on Crystal Growth Rate in Multiparticle Agitated Crystallizers
- CVD Synthesis of Alumina-supported Molybdenum Carbide Catalyst
- Effect of Initial Supersaturation on Mechanism of Purity Drop during Preferential Crystallization
- PURIFICATION BY SWEATING OF ORGANIC SOLID SOLUTIONS BY LAYER AND SUSPENSION TYPE MELT CRYSTALLIZATION OPERATIONS
- FT-IR Study on the Effect of Solvents on Polymorphic Crystallization of Organic Compounds
- Kinetic Study on Polymorphic Solid-State Transformation of Organic Compounds : Bisphenol A and DL-Methionine
- Agglomeration Kinetics and Product Purity of Sodium Choloride Crystals in Batch Crystallization
- Purity of m-Chloronitrobenzene Agglomerates from Batch Seeded Suspension Crystallization
- Effect of Face Crystallographic Orientation of Seed Crystal on Purity Drop during Preferential Crystallization
- Etch Rate Distribution over Silicon Wafers in EPW Solutions : Semiconductors and Semiconductor Devices
- Secondary Growth Phenomena in Industrial Crystallization and Their Effects on Crystal Quality
- PREPARATION OF SILICON THIN DIAPHARAGMS FREE FROM MICROPYRAMIDS USING ANISOTROPIC ETCHING IN KOH SOLUTIONS
- Kinetics of Solid State Polymorphic Transition of Caffeine
- Solid-State Recrystallization Behavior of Binary Inorganic Salt Systems by Mechanochemical Processing
- Surface Phenomena and Mechanism of Polymorphic Transition in Theophylline
- Surface modification of silica particles with polyimide by ultrasonic wave irradiation
- Surface modification of silica particles using polyimide
- Study of polyimide particle surface modification by the high-speed impact method
- A Continuous Production Method of Nano-Particles of Leucine by Controlled Nucleation and Growth in Ternary Systems
- Effect of Washing L-Threonine Seed Crystals on Surface Nucleation of D-Threonine
- Solid-State Crystallization Behavior of Tetrabenzoporphyrin Organic Semiconductors
- Kinetics of Humidity Driven Solid-State Polymorphic Transition of Theophylline Anhydrates
- Controlled Production of Polymorphic Mixtures of MPPO in Batch Cooling and Drowning-Out Crystallization
- NaCl Crystal Growth Rate under Conditions of Continuous Slurry Feeding
- On the Size of Critical Nuclei and Growth Units of Zeolite A during Phase Transformation from Aluminosilicate Solutions
- Effects of Undersaturation on Crystal Size Distribution in Cooling Type Batch Crystallization
- Composition of solid condensate on a cold surface from a mixed organic vapor.
- A combined crystallization process to separate binary organic eutectic mixtures.
- PHENOMENA OF SOLIDIFICATION IN NORMAL FREEZING OF A SIMPLE EUTECTIC-FORMING ORGANIC MELT
- Rate of solid condensation from organic vapors on a cold surface.
- Purification of p-dichlorobenzene and m-chloronitrobenzene crystalline particles by sweating.
- The separation of eutectic forming organic mixtures by normal freezing.
- Rate of composition changes of organic solid solution crystals in sweating operations.
- Nucleation and growth of nuclei from organic vapors on a cold surface.