Immunohistochemical Study of Multiple Inflammatory Pseudotumors With Both Brain and Spinal Cord Involvement : Case Report
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概要
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A 55-year-old man presented with a rare case of both intracranial and intraspinal inflammatory pseudotumors manifesting as progressive motor weakness in his lower extremities. Magnetic resonance imaging revealed a 24-mm diameter tumor-like lesion in the left parietal lobe and an intramedullary 24-mm diameter lesion at the C7 and T1 levels of the spinal cord. These lesions were resected by sequential operations. Histological examination of the resected lesions revealed the presence of excessive collagen fibers infiltrated with polyclonal lymphocytes and plasma cells, and the diagnosis was inflammatory pseudotumor. Immunohistochemical staining with anti-immunoglobulin G4 (IgG4) antibody found no accumulation of IgG4-positive cells. The serum IgG4 level was normal. Thus, this case did not meet the criteria for IgG4-related disease.
- 2010-03-15
著者
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YOSHIMINE Toshiki
Department of Neurosurgery, Osaka University Medical School
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ISHIHARA Masahiro
Department of Neurosurgery, Osaka University Graduate School of Medicine
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IZUMOTO Shuichi
Department of Neurosurgery, Hyogo College of Medicine
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IWATSUKI Koichi
Department of Neurosurgery, Osaka University Graduate School of Medicine
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Yoshimine Toshiki
Department Of Neurosurgery Osaka University Graduate School Of Medicine
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Yoshimine Toshiki
Department Of Neurosurgery Osaka University Medical School
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Iwatsuki Koichi
Department Of Neurosurgery Osaka University Graduate School Of Medicine
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Yoshimine Toshiki
Department Of Neurosurgery Course Of Interventional Medicine (e1) Osaka University Graduate School O
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Izumoto Shuichi
Department Of Neurosurgery Hyogo College Of Medicine
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Ishihara Masahiro
Department Of Neurosurgery Osaka University Graduate School Of Medicine
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Ishihara Masahiro
Department Of Advanced Nuclear Heat Technology Japan Atomic Energy Research Institute
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