Early-Stage Goniodysgenetic Glaucoma in a Young Beagle Dog

概要

論文の詳細を見る
Signs of glaucoma such as greenish eyes were observed clinically in a 9-month-old male beagle dog. Histopathologically, the glaucomatous eye was characterized by goniodysgenesis (the absence of a trabecular meshwork) in the filtration angle. Spheroid bodies suggestive of axonal degeneration were observed in the axons posterior to the lamina cribrosa, although cupping of the optic nerve head was not seen. The diagnosis of early-stage glaucoma due to goniodysgenesis was made based on the animals clinical course and histopathological findings. In addition, narrowing of the episcleral veins, fluid retention in the ciliary processes, and retinal edema were noted. The above findings support the concept that glaucomatous optic neuropathy may be caused by a reduction in blood flow rather than an increase in intraocular pressure.
日本毒性病理学会の論文
2004-12-30