Glucose-6-Phosphate Dehydrogenase (G6PD) Variants in Three Minority Ethnic Groups in Central and Northern Vietnam
スポンサーリンク
概要
- 論文の詳細を見る
Community-based surveys for the detection of glucose-6-phosphate dehydogenase (G6PD) deficiency were conducted at three villages in central and northern Vietnam from 2001 to 2006. A total of 799 male individuals belonging to three ethnic groups (Raglai, Pako, and Khomu) were tested for G6PD enzyme activity and 32 G6PD deficient individuals were detected. The prevalence of G6PD deficiency in Raglai, Pako, and Khomu was 2.1% (9⁄438), 7.7% (16⁄208), and 4.6% (7⁄153), respectively. In Raglai, G6PD Viangchan was found to be dominant (8⁄9, 88.9%), followed by G6PD Canton (1⁄9, 11.1%). In Pako, a total of 16 G6PD deficient cases showed G6PD Viangchan variant. All analyzed samples (7⁄7, 100%) showed the G6PD Union variant in the Khomu ethnic group. Our study suggests that the Raglai and Pako people share a common ancestry with Cambodians, Laotians, and Thais. On the other hand, the appearance of G6PD Union among Khomu people suggests that they originate from a different ancestry.
- 2009-03-01
著者
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Tinh Ta
National Inst. Of Malariology Parasitology And Entomology
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Ta Thi
東京女子医科大学 国際環境･熱帯医学分野
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Tinh Ta
National Institute Of Malariology Parasitology And Entomology
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MINH HUNG
Department of International Affairs and Tropical Medicine, Tokyo Women's Medical University
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MATSUOKA Hiroyuki
Division of Medical Zoology, Department of Infection and Immunity, Jichi Medical University
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ETO Hideaki
Department of International Affairs and Tropical Medicine, Tokyo Women's Medical University
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MITA Toshihiro
Department of International Affairs and Tropical Medicine, Tokyo Women's Medical University
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DAO Le
National Institute of Malariology, Parasitology, and Entomology
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TRUNG Pham
National Institute of Malariology, Parasitology, and Entomology
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PHUONG Vo
National Institute of Malariology, Parasitology, and Entomology
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MARMA Aung
Department of International Affairs and Tropical Medicine, Tokyo Women's Medical University
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KOBAYAKAWA Takatoshi
Department of International Affairs and Tropical Medicine, Tokyo Women's Medical University
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Mita Toshihiro
Department Of International Affairs And Tropical Medicine Tokyo Women's Medical University
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Mita Toshihiro
Department Of Gastroenterology And Hepatology Jikei Medical University School Of Medicine
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Dao Le
National Institute Of Malariology Parasitology And Entomology
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Phuong Vo
National Institute Of Malariology Parasitology And Entomology
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Minh Hung
Department Of International Affairs And Tropical Medicine Tokyo Women's Medical University
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Trung Pham
National Institute Of Malariology Parasitology And Entomology
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Marma Aung
Department Of International Affairs And Tropical Medicine Tokyo Women's Medical University
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Eto Hideaki
Department Of International Affairs And Tropical Medicine Tokyo Women's Medical University
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Matsuoka Hiroyuki
Division Of Medical Zoology Department Of Infection And Immunity Jichi Medical University
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Kobayakawa Takatoshi
Department Of International Affairs And Tropical Medicine Tokyo Women's Medical University
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Eto Hideaki
Department Of International Affairs And Tropical Medicine Faculty Of Medicine Tokyo Women's Med
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