Proteomic Trajectory Mapping : タンパク質発現軌跡地図

概要

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In the previous article we introduced two concepts in sémiotique to be used in the area of comparative physiology and biochemistry; synchronie and diachronie. The former describes a snapshot of a complex biological system taken at a certain time point, whereas the latter describes the dynamic aspect of a complex biological system through time. In order to achieve the latter it is necessary to study the time-dependent change of system parameters such as kinetics of protein expression. We have established a methodology to trace the dynamic aspect of protein expression for as many as several hundred proteins and called it “proteomic trajectory mapping.” In this follow-up review we will explain proteomic trajectory mapping in detail which is essential for studying the diachronic aspect of living things.
2008-11-20