人間ドック健診者における大脳MRI皮質下白質変化と重心動揺成績

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To investigate the relationship between white matter lesions identified on MRI and balance dysfunction in elderly persons, we evaluated findings on brain MRI and body sway examined with a stabilometer in persons (n=49) aged over 50 years old who were hospitalized for a thorough medical checkup. The total number and major axes of spots indicating deep white matter, hyperintense signals (DWMH) on MRI were measured. If the total number of spots exceeded 10 or the major axes exceeded 4 mm, white matter changes were judged to be severe. Sway of the body is center of gravity was recorded with eyes open and closed for 60 seconds using a stabilometer. The sway area and locus length, as well as left-right (X position) and forward-backward (Y position) deviation of the center of sway were measured. The measurements regarding these parameters were compared with standard values in healthy subjects. Persons with normal values in all 4 parameters (sway area and right-left deviation with eyes open and closed) were regarded as stable, and persons with values beyond the normal range were regarded as unstable. Elderly persons with severe white matter lesions on MRI identified on a thorough medical checkup were significantly unstable. We suggested that elderly persons with severe white matter lesions tended to exhibit postural abnormalities due to brain arteriolosclerosis.Tokita proposed the usefullness of stabilometry on health examination to check the health condition and detect any signs of Cerebrovascular disorders. We believe that our results also showed the utility of stabilometry in health examinations.
日本めまい平衡医学会の論文
2007-06-01

人間ドック健診者における大脳MRI皮質下白質変化と重心動揺成績

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