Identification and Analysis of Ku70 and Ku80 Homologs in the koji Molds Aspergillus sojae and Aspergillus oryzae
スポンサーリンク
概要
- 論文の詳細を見る
Ku genes play a key role in the non-homologous end-joining pathway. We have identified Ku70 and Ku80 homologs in the koji molds Aspergillus sojae and Aspergillus oryzae, and have constructed the disruption mutants of Ku70, Ku80, and Ku70–80 to characterize the phenotypic change in these mutants. Neither Ku70- nor Ku80-disrupted strains show hypersensitivity to the DNA damaging agents methylmethane sulfonate (MMS) and phleomycin. Moreover, undesirable phenotypes, such as poor growth or repressed conidiospore formation, were not observed in the Ku-disrupted A. sojae and A. oryzae.
- 社団法人 日本農芸化学会の論文
- 2006-01-23
著者
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TAKAHASHI Tadashi
Noda Inst. Sci. Res.
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KOYAMA Yasuji
Noda Inst. Sci. Res.
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Koyama Yasuji
Noda Institute For Scientific Research
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Masuda Tsutomu
Noda Institute For Scientific Research
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Koyama Yasuji
Noda Inst. For Scientific Res.
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Takahashi Tadashi
Noda Inst. For Scientific Res.
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