Hepatoprotective Effects of Whey Protein on D-Galactosamine-Induced Hepatitis and Liver Fibrosis in Rats

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概要

• 論文の詳細を見る

• The hepatoprotective effects of whey protein on two injections of D-galactosamine (300 mg/kg, i.p.) were investigated in rats fed a modified AIN-93M diet formulated with a protein source of casein or whey for 16 d. The whey protein-containing diet clearly suppressed an increase in plasma alanine and aspartate aminotransferase activity, lactate dehydrogenase and bilirubin, which are hepatitis markers, and also hyaluronic acid, a fibrosis marker. In addition, it suppressed histopathological signs of portal fibrosis, bile duct proliferation, and perivenular sclerosis. These results suggest that supplementation with whey protein can help prevent the development of hepatitis and portal fibrosis.

• 社団法人 日本農芸化学会の論文
• 2006-05-23

著者

• Sasaki Hajime

  Department Of Electronics Faculty Of Engineering Tottori University

• Sasaki Hajime

  Department Of Nutritional Research Food Science Institute Meiji Dairies Corporation

• Kume Hisae

  Department Of Nutritional Research Food Science Institute Meiji Dairies Corporation

• OKAZAKI Keiko

  Department of Nutritional Research, Food Science Institute, Meiji Dairies Corporation

• Okazaki Keiko

  Department Of Nutritional Research Food Science Institute Meiji Dairies Corporation

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