Synthesis and Triplex-Forming Ability of 2', 4'-BNAs Bearing Imidazoles as a Nucleobase
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概要
- 論文の詳細を見る
To expand the sequence of double-stranded DNA (dsDNA) targets in a triplex formation, 2',4'-BNAs (2'-O,4'-C-methylene bridged nucleic acids) having imidazoles as a nucleobase were synthesized and incorporated into oligonucleotides. Triplex-forming ability of the modified oligonucleotides was evaluated by using melting temperature (T_m) measurements.
- 公益社団法人日本薬学会の論文
- 2005-07-01
著者
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Obika Satoshi
Graduate School of Pharmaceutical Sciences, Osaka University
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Imanishi Takeshi
Graduate School of Pharmaceutical Sciences, Osaka University
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Imanishi Takeshi
Graduate School Of Pharmaceutical Sciences Osaka University
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Obika Satoshi
Graduate School Of Pharmaceutical Sciences Osaka University
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Obika Satoshi
大阪大学 薬研究
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Imanishi Takeshi
Osaka Univ. Osaka Jpn
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HARI Yoshiyuki
Graduate School of Pharmaceutical Sciences, Osaka University
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INOHARA Hiroyasu
Graduate School of Pharmaceutical Sciences, Osaka University
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IKEJIRI Masahiro
Graduate School of Pharmaceutical Sciences, Osaka University
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UNE Daisuke
Graduate School of Pharmaceutical Sciences, Osaka University
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Hari Yoshiyuki
Graduate School Of Pharmaceutical Sciences Osaka University
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Une Daisuke
Graduate School Of Pharmaceutical Sciences Osaka University
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Inohara Hiroyasu
Graduate School Of Pharmaceutical Sciences Osaka University
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Ikejiri Masahiro
Graduate School Of Pharmaceutical Sciences Osaka University
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