Longicalycinin A, a New Cytotoxic Cyclic Peptide from Dianthus superbus var. longicalycinus (MAXIM.) WILL
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概要
- 論文の詳細を見る
A new cyclic peptide, longicalycinin A (1), and six known compounds, vaccaroside A, dianoside A, dianoside G, 3-(4-hydroxy-3-methoxy-phenyl)propionic acid methyl ester, p-hydroxybenzoic acid, and p-hydroxybenzaldehyde were isolated from the MeOH extract of Dianthus superbus var. longicalycinus. The amino acid sequences of 1 was elucidated as cyclo(Gly^1-Phe^2-Tyr^3-Pro^4-Phe^5-) on the basis of ESI tandem mass fragmentation analysis, chemical evidence, and extensive 2D NMR methods. Furthermore, compound 1 showed cytotoxicity to Hep G2 cancer cell line.
- 公益社団法人日本薬学会の論文
- 2005-03-01
著者
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Chang F‐r
Graduate Institute Of Natural Products College Of Pharmacy Kaohsiung Medical University:center Of Ex
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Wu C‐c
Graduate Institute Of Natural Products Kaohsiung Medical University
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Wu Yang-chang
Graduate Inst. Of Natural Products Kaohsiung Medical Univ.
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Wu Yang
Graduate Institute Of Natural Products Kaohsiung Medical College
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YEN Hsin-Fu
National Museum of Natural Science
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HSIEH Pei-Wen
Graduate Institute of Natural Products, Chang Gung University
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HSIEH Pei
Graduate Institute of Natural Products, Kaohsiung Medical University
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CHANG Fang
Graduate Institute of Natural Products, Kaohsiung Medical University
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WU Ching
Graduate Institute of Natural Products, Kaohsiung Medical University
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LI Chien
Divisions of Environmental Health and Occupational Medicine, National Health Research Institute
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WU Kuen
Divisions of Environmental Health and Occupational Medicine, National Health Research Institute
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CHEN Su
Graduate Institute of Natural Products, Kaohsiung Medical University
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YEN Hsin
National Museum of Natural Science
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Hsieh Pei
Graduate Institute Of Natural Products Chang Gung University
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Hsieh P‐w
Institute Of Marine Resources National Sun Yat-sen University
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Chang Fang-rong
Graduate Inst. Of Natural Products Coll. Of Pharmacy Kaohsiung Medical Univ.
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Chang Fang
Graduate Institute Of Natural Products College Of Pharmacy Kaohsiung Medical University:center Of Ex
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Chen Su
Graduate Institute Of Natural Products Kaohsiung Medical University
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Wu Kuen
Divisions Of Environmental Health And Occupational Medicine National Health Research Institute
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Li Chien
Divisions Of Environmental Health And Occupational Medicine National Health Research Institute
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Hsieh Pei-wen
Graduate Institute Of Natural Products Chang Gung University
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Wu Ching-Chung
Graduate Institute of Natural Products, Kaohsiung Medical University
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Wu Ching
Graduate Institute Of Natural Products Kaohsiung Medical University
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