腎臓における副甲状腺ホルモン関連ペプチドの局在の検討

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概要

• 論文の詳細を見る

• PTHrP mRNA was quantified by RT-PCR and the localization of PTHrP mRNA was determined by in situ hybridization in kidney. During development, the expression of PTHrP mRNA is much higher before 2 weeks of age while kidney is developing. In E16 fetal mice, PTHrP mRNA was strongly expressed in the collecting ducts, urothelium of the pelvis, tubles, the glomeruli and immature elements in the cortex of the developing kidney (nephrogenic zone). within 0-day-old-mice, it was dominantly expressed in collecting ducts, the urothelium of the pelvis and nephrogenic zone. These findings suggest that PTHrP plays a role in kidney development as an autocrine/ paracrine factor.

• 岡山医学会の論文
• 1997-12-25

著者

• 綾 邦彦

  岡山大学医学部　小児科

• 綾 邦彦

  岡山大学医学部小児科学講座

関連論文

• PTHrPの腎における発現
• 腎臓における副甲状腺ホルモン関連ペプチドの局在の検討
• ビタミンD依存性くる病1型と2型 (特集 分子内分泌学)

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