キラルな1, 2-ジアミンを用いるアルコール類の触媒的不斉アシル化の開発
スポンサーリンク
概要
- 論文の詳細を見る
Asymmetric acylation of alcohols is very important in synthetic organic chemistry and holds great potential for the preparation of small chiral compounds which are suited for further manipulation in the synthesis of biologically active natural products. Although enzymatic acylation has been extensively studied and established as a promising method for the preparation of chiral alcohol variants, development of nonenzymatic alternatives in this field has been scattered. From this viewpoint, we wish to demonstrate highly efficient and practical methods for the catalytic asymmetric acylation of racemic secondary alcohols and various <I>meso</I>-diols by the reaction with achiral benzoyl chloride in the presence of a chiral 1, 2-diamine derived from (<I>S</I>) -proline.
- 社団法人 有機合成化学協会の論文
- 1999-07-01
著者
関連論文
- 106(P-28) キラルな1,2-ジアミンを用いるアルコール類の触媒的不斉アシル化(ポスター発表の部)
- Catalytic Asymmetrization of cis-2-Cyclopentene-1,4-Diol. Highly Efficient and Practical Synthesis of (R)-4-Benzoyloxy-2-Cyclopenten-1-one
- 茨城大学サイエンステクノロジーフェスタ2009
- キラルな1, 2-ジアミンを用いるアルコール類の触媒的不斉アシル化の開発
- Catalytic Asymmetric Acylation of Racemic Scondary Alcohols with Benzoyl Chloride in the Presence of a Chiral Diamine
- アルデヒドおよびアセタールからの新規複合型アリル化反応
- 105(P-26) Sc(OTf)_3を用いたアルコールの新規シリルエーテル化(ポスター発表の部)
- 精密合成における高効率ワンステップ保護基変換反応
- MS 4A存在下でのDMSOの特性に着目した無触媒反応の開発