精密合成における高効率ワンステップ保護基変換反応

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概要

• 論文の詳細を見る

• A great number of protective groups for hydroxyl function have played an important role in organic synthesis particularly in the degradation or transformation of natural products and in the synthesis of polyfunctional molecules. Various types of protective groups for hydroxyl function have been exploited and are classified mostly into alkyl ether-, silyl ether-, acetal-, and ester-types. It is frequently needed to transform an existing protective group to another one pretinent to the following steps in the course of total synthesis of complex natural products such as carbohydrates and macrolide antibiotics, and this usually calls for two separate steps, i.e. a deprotection and a protection-anew. It will therefore be of great benefit in view of time and material savings to have means of one-step transformations between protective groups. From this viewpoint, I wish to demonstrate novel and efficient methods for one-step conversion of protective groups of hydroxyl function.

• 社団法人 有機合成化学協会の論文
• 1996-06-01

著者

• 折山 剛

  茨城大 理

• 折山 剛

  茨城大学理学部

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