An Implication of Molecular Mechanism for Eliciting Sweetness of Anionic β-Glycyrrhetinic Acid Derivatives
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概要
- 論文の詳細を見る
Anionic derivatives of β-glycyrrhetinic acid (GA) containing a carboxylate- and a sulfate-terminated substituent at the C-3 position were prepared and assessed for their relative sweetness. A molecular mechanism for sweet taste expression of these derivatives was discussed assuming CPK molecular models of the N-terminal α-helix fragment of the T1R3 protein, which was a likely candidate for the binding site of GA derivatives and helped well explain their sweetness.
- 2002-05-01
著者
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Tamagaki Seizo
Department Of Applied & Bioapplied Chemistry Graduate School Of Engineering Osaka City Universit
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Tamagaki Seizo
Department Of Bioapplied Chemistry Graduate School Of Engineering Osaka City University
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TOYOSHIMA Toshinobu
Department of Bioapplied Chemistry, Graduate School of Engineering, Osaka City University
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FUJIHARA Masahiro
Department of Bioapplied Chemistry, Graduate School of Engineering, Osaka City University
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Toyoshima Toshinobu
Department Of Bioapplied Chemistry Graduate School Of Engineering Osaka City University
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Fujihara Masahiro
Department Of Bioapplied Chemistry Graduate School Of Engineering Osaka City University
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