Characteristics of Spontaneous Erythema Appeared in Hairless Rats
スポンサーリンク
概要
- 論文の詳細を見る
The hairless rat (WBN/Kob-Ht), a dominant mutant rat derived from the Wistar strain, rarely develops spontaneous erythema of a progressive nature on its skin. Erythema was first observed at 8 weeks of age and the incidence at 20 weeks of age was about 4% in both males and females. Histopathologically, erythema was characterised by dermatitis induced by an immunological reaction. Areas of erythema in the skin were decreased by treatment with dexamethasone (1 mg/kg) or ciclosporin (25 or 50 mg/kg). These results suggested that erythema on the hairless rat could be used as an animal model of spontaneous dermatitis.
- 社団法人 日本実験動物学会の論文
- 1998-10-01
著者
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NOGUCHI Makoto
Department of Neurosurgery, Faculty of Medicine, University of Tokyo
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Tani Satoru
Life Sciences Research Center And Faculty Of Pharmaceutical Sciences Josai University
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HOSODA Yukihide
JAC
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SUGIBAYASHI Kenji
Life Sciences Research Center and Faculty of Pharmaceutical Sciences, Josai University
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MORIMOTO Yasunori
Life Sciences Research Center and Faculty of Pharmaceutical Sciences, Josai University
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Noguchi M
Department Of Dermatology School Of Dentistry Meikai University
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Morimoto Yasunori
Life Sciences Research Center And Faculty Of Pharmaceutical Sciences Josai University
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Sugibayashi Kenji
Life Sciences Research Center And Faculty Of Pharmaceutical Sciences Josai University
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Noguchi Makoto
Department Of Applied Biotechnology Food Developing Laboratory Tottori Institute Of Industrial Techn
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