Sequence Analysis of Major Structural Proteins of Newly Isolated Mouse Hepatitis Virus

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概要

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• We have isolated the virus from a fecal pellet in the colon of a BALB/c mouse with X-linked immunodeficiency (xid) housed in a room in which there has recently been an epidemic due to mouse hepatitis virus (MHV) and designated it as the MHV-TY strain. Sequence analysis of the MHV-TY strain was performed on major structural, spike (S), membrane (M) and nucleocapsid (N), proteins directly from PCR products. The comparison of nucleotide sequences of MHV-TY with other strains investigated so far revealed that all three structural proteins of the TY strain had some unique amino acid sequences among MHV strains which can be used as markers of this strain.

• 社団法人　日本実験動物学会の論文

著者

• YAMADA Yasuko

  Division of Experimental Animal Research, National Institute of Infectious Diseases

• YABE Mikiko

  Division of Experimental Animal Research, National Institute of Infectious Diseases

• Yabe Mikiko

  Division Of Experimental Animal Research National Institute Of Infectious Diseases

• Yamada Y

  National Inst. Infectious Diseases Tokyo Jpn

• Yamada Yasuko

  Division Of Experimental Animal Research National Institute Of Infectious Diseases

関連論文

• 精製組換え核タンパク質を用いたELISAによるリンパ球性脈絡髄膜炎ウイルス標準株および分離株に対する抗体の検出
• Application of Nested Polymerase Chain Reaction to Detection of Mouse Hepatitis Virus in Fecal Specimens during a Natural Outbreak in an Immunodeficient Mouse Colony
• Contamination of Mouse-adapted Influenza Virus with Sendai Virus
• Detection of MHV-RNAs in Mouse Intestines and in Filter Dust in Mouse Room Ventilation Duct by a Modified RT-Nested PCR
• Sequence Analysis of Major Structural Proteins of Newly Isolated Mouse Hepatitis Virus
• Effect of Hypochlorite-Based Disinfectants on Inactivation of Murine Norovirus and Attempt to Eliminate or Prevent Infection in Mice by Additionto Drinking Water

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