Time-Dependent Apoptotic Development and Pro-apoptotic Genes Expression in Rat Heart After Myocardial Infarction
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概要
- 論文の詳細を見る
We investigated the apoptotic development and apoptotic-related gene expression after myocardial infarction (MI) at different time points in the current study. Bax gene expression was increased at 12 h after MI and peaked at 24 h. Fas gene started to over-express at 12 h after MI as well but it reached maximum at 72 h. In the MI groups, strongest staining of apoptosis was detected in rats 3 days post operation. Our results demonstrate that apoptotic development after MI is time dependent in the ischemic area and there could be some linkage with the over expression of angiotensin II receptors post MI.
- 社団法人 日本薬理学会の論文
- 2001-07-01
著者
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Unger T
Department Of Pharmacology University Of Kiel
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Unger Thomas
Department Of Pharmacology Christian-albrechts University Of Kiel Hospitalstrabe4 24105 Kiel And Ger
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Lu Qing
Department Of Echocardiography Union Hospital Tongji Medical College Huazhong University Of Science
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Lu Qing
Department Of Pharmacology National University Of Singapore
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ZHU Yi
Department of Pharmacology, National University of Singapore
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ZHU Yi-Chun
Department of Physiology, Shanghai Medical University
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WANG Zhong
Department of Pharmacology, National University of Singapore
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LEE How
Department of Pharmacology, National University of Singapore
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Wang Zhong
Department Of Pediatric Surgery Kagawa Medical University
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Zhu Yi
Department Of General Surgery The First Affiliated Hospital Of Nanjing Medical University
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Lee How
Department Of Pharmacology National University Of Singapore
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Zhu Yi
Department Of Pharmacology National University Of Singapore
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Wang Zhong
Department Of Pharmacology National University Of Singapore
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Wang Zhong
Department Of Electrical And Electronics Engineering Kobe University
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WANG Zhong
Department of Anatomy and Embryology, Ehime University Graduate School of Medicine
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ZHU Yi-Chun
Department of Pharmacology, Christian-Albrechts University of Kiel, 24105 Kiel, Germany.
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