Lupus Anticoagulant in Myasthenia Gravis Associated with IgM Gammopathy
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概要
- 論文の詳細を見る
The plasma of a patient with myasthenia gravis had strong lupus anticoagulant activity and his IgM paraprotein displayed non-specific inhibition to coagulation factors IX, XI, XII, prekallikrein, and high molecular weight kininogen. He was placed on prednisolone, which resulted in improvement in his myasthenic symptoms, but the prolongation of APTT and macroglobulinemia remained. Double filtration plasmapheresis successfully decreased the serum IgM level from 1, 190 mg/dl to 375 mg/dl and APTT improved from 58 s to 38 s. Myasthenia gravis is frequently associated with other autoimmune diseases, but the association with lupus anticoagulant and IgM gammopathy is rare.(Internal Medicine 40: 952-955, 2001)
- 社団法人 日本内科学会の論文
著者
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Komiyama Yutaka
The Department Of Clinical Sciences And Laboratory Medicine Kansai Medical University
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IKEDA Shu-ichi
the Department of Medicine (Neurology), Shinshu University School of Medicine
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ISHIKAWA Shozo
the Department of Medicine (Neurology), Shinshu University School of Medicine
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KOBAYASHI Hikaru
the Department of Hematology
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TSUYUZAKI Jun
the Department of Medicine (Neurology), Shinshu University School of Medicine
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TOKUNAGA Shinichi
the Department of Nephrology
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MIYAZAKI Atsushi
the Department of Dermatology
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HANYU Norinao
the Department of Neurology, Nagano Red-Cross Hospital
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Ikeda Shu-ichi
The Department Of Medicine (neurology) Shinshu University School Of Medicine
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Hanyu Norinao
The Department Of Neurology Nagano Red-cross Hospital
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Tsuyuzaki Jun
The Department Of Medicine (neurology) Shinshu University School Of Medicine
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Ishikawa Shozo
The Department Of Medicine (neurology) Shinshu University School Of Medicine
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