Simultaneous Measurement of Pulmonary Diffusing Capacity for CO and Cardiac Output by a Rebreathing Method in Patients with Pulmonary Diseases
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概要
- 論文の詳細を見る
Pulmonary diffusing capacity for CO (DLCO) and cardiac output (Q) were simultaneously measured by a noninvasive rebreathing method (RB) in 15 normal subjects and in 60 patients, including cardiac diseases (CD), bronchial asthma (BA), chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (PF). DLCO and Q were tested by the single breath method (SB) and the dye-dilution method (Dye), respectively. DLCO(RB) correlated well with DLCO (SB) (r=0.890, p<0.001). Q(RB) also correlated well with Q(Dye) (r=0.909, p<0.001). Factors affecting DLCO (RB) were age, height, body surface area, O2 consumption, Q, hematocrit (Hct) and Q&built;Hct, among which Q&built;Hct was the prominent influential determinant. DLCO per lung volume was smaller in COPD and PF than in BA or healthy subjects, while, the ratio of DLCO/(Q&built;Hct) was significantly higher in COPD than in PF. Simultaneous measurements of DLCO and Q offer comprehensive characterization for functional changes in lung parenchyma.(Internal Medicine 34: 330-338, 1995)
- 社団法人 日本内科学会の論文
著者
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TOMOIKE Hitonobu
The First Dep. of Internal Medicine, Yamagata University School of Medicine
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Tomoike Hitonobu
The First Department Of Internal Medicine Yamagata University School Of Medicine
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Uchida Katsuo
The First Department Of Physiology
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TAKAHASHI HIFUMI
The First Department of Internal Medicine, Yamagata University School of Medicine
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IWABUCHI Katsuyoshi
the First Department of Internal Medicine
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KUDO Yukiharu
the First Department of Internal Medicine
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NIIZEKI Kyuichi
the First Department of Physiology
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TAKAHASHI Keiji
the Department of Laboratory Medicine, Yamagata University School of Medicine
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Takahashi Hifumi
The First Department Of Internal Medicine
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Tomoike Hitonobu
The First Department Of Internal Medicine
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Takahashi Keiji
The Department Of Laboratory Medicine Yamagata University School Of Medicine
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