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Pharmacology Research Laboratories I Pharmaceutical Research Division Takeda Chemical Industries Ltd | 論文
- Stability and Stabilization Studies of TAK-599 (Ceftaroline Fosamil), a Novel N-Phosphono Type Prodrug of Anti-methicillin Resistant Staphylococcus aureus Cephalosporin T-91825
- Optically Active Antifungal Azoles. XII. Synthesis and Antifungal Activity of the Water-Soluble Prodrugs of l-[(lR, 2R)-2-(2, 4-Difluorophenyl)-2-hydroxy-l-methyl-3-(1H-1, 2, 4-triazol-1-yl)propyl]3-[4-(lH-1-tetrazolyl)phenyl]-2-imidazolidinone
- Optically Active Antifungal Azoles. X. Synthesis and Antifungal Activity of N-[4-(Azolyl)phenyl]- and N-[4-(Azolylmethyl)phenyl]-N'-[(1R, 2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-azolones
- Arborcandins A, B, C, D, E and F, Novel 1,3-β-Glucan Synthase Inhibitors : Physico-chemical Properties and Structure Elucidation
- F-10748 A_1, A_2, B_1, B_2, C_1, C_2, D_1 and D_2, Novel Papulacandins
- Arborcandins A, B, C, D, E and F, Novel 1,3-β-G1ucan Synthase Inhibitors : Production and Biological Activity
- Orally Active CCR5 Antagonists as Anti-HIV-1 Agents : Synthesis and Biological Activity of 1-Benzothiepine 1, 1-Dioxide and 1-Benzazepine Derivatives Containing a Tertiary Amine Moiety
- Optically Active Antifungal Azoles. VIII. Synthesis and Antifungal Activity of 1-[(1R, 2R)-2-(2,4-Difluoro- and 2-Fluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-3-(4-substituted phenyl)-2(1H, 3H)-imidazolones and 2-Imidazolidinones
- Optically Active Antifungal Azoles. VII. Synthesis and Antifungal Activity of Stereoisomers of 2-[(1R, 2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-[4-(2,2,3,3-tetrafluoropropoxy)phenyl]-3(2H, 4H)-1,2,4-triazolone (TAK-
- Optically Active Antifungal Azoles. VI. Synthesis and Antifungal Activity of N-[(1R, 2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-N'-(4-substituted phenyl)-3(2H, 4H)-1,2,4-triazolones and 5(1H, 4H)-tetrazolones
- Orally Active CCR5 Antagonists as Anti-HIV-1 Agents 2 : Synthesis and Biological Activities of Anilide Derivatives Containing a Pyridine N-Oxide Moiety
- CCR5 Antagonists as Anti-HIV-1 Agents.1. Synthesis and Biological Evaluation of 5-Oxopyrrolidine-3-carboxamide Derivatives
- Asymmetric Transfer Hydrogenation Catalyzed by Diamine - Iridium(I)Complexes
- In vitro antimicrobial activity of T-91825, a novel anti-MRSA cephalosporin, and in vivo anti-MRSA activity of its prodrug, TAK-599
- Studies on Anti-MRSA Parenteral Cephalosporins : IV. A Novel Water-soluble N-Phosphono Type Prodrug for Parenteral Administration
- Studies on Anti-MRSA Parenteral Cephalosporins : III. Synthesis and Antibacterial Activity of 7β-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2(Z)-alkoxyiminoacetamido]-3-[(E)-2-(1-alkylimidazo[1,2-b]pyridazinium-6-yl)thiovinyl]-3-cephem-4-carboxylates and Related
- Studies on Anti-MRSA Parenteral Cephalosporins : II. Synthesis and Antibacterial Activity of 7β-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2(Z)-alkoxyiminoacetamido]-3-(substituted imidazo[1,2-b]pyridazinium-1-yI)methyl-3-cephem-4-carboxylates and Related Compoun
- Studies on Anti-MRSA Parenteral Cephalosporins : I. Synthesis and Antibacterial Activity of 7β-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2(Z)-hydroxyiminoacetamido]-3-(substituted imidazo[1,2-b]-pyridazinium-1-yl)methyl-3-cephem-4-carboxylates and Related Compou
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