LANYI Arpad | Division of Immunology, Beth Israel Deaconess Medical Center, Harvard Medical School
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- Division of Immunology, Beth Israel Deaconess Medical Center, Harvard Medical Schoolの論文著者
Division of Immunology, Beth Israel Deaconess Medical Center, Harvard Medical School | 論文
- Potential pathways for regulation of NK and T cell responses: differential X-linked lymphoproliferative syndrome gene product SAP interactions with SLAM and 2B4
- SAP increases FynT kinase activity and is required for phosphorylation of SLAM and Ly9
- Activation-induced apoptosis of mature T cells is dependent upon the level of surface TCR but not on the presende of the CD3ζ ITAM
- Generation of antigen-specific cytotoxic T lymphocytes and regulation of cytokine production takes place in the absence of CD3ζ
- Expression of a CD3ε transgene in CD3εnull mice does not restore CD3γ and δ expression bur efficienly rescues T cell development from a subpopulation of prothymocytes