Shigematsu Nobuharu | Exploratory Research Division Astellas Research Technologies

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著作論文

Total Synthesis of WS9326A, a Potent Tachykinin Antagonist from Streptomyces violaceoniger
Site-specific Structural Transformation of the Novel Antifungal Cyclic Depsipeptide FR901469 : Synthesis and Biological Activity of FR203904
FR901469, a Novel Antifungal Antibiotic from an Unidentified Fungus No. 11243 : III. Structure Determination
FR901483, a Novel Immunosuppressant Isolated from Cladobotryum sp. No. 11231 Taxonomy of the Producing Organism, Fermentation, Isolation, Physico-chemical Properties and Biological Activities
The Novel Gluconeogenesis Inhibitors FR225659 and FR225656 from Helicomyces sp. No. 19353 : III. Structure Determination
FR225659-binding Proteins : Identification as Serine/Threonine Protein Phosphatase PP1 and PP2A Using High-performance Affinity Beads
Cloning and heterologous expression of P450Um-1, a novel bacterial P450 gene, for hydroxylation of immunosuppressive agent AS1387392

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