Matsuhisa Akira | Institute For Drug Discovery Research Astellas Pharma Inc.

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著作論文

2-(3-Pyridyl)thiazolidine-4-carboxamides. 1. Novel Orally Active Antagonists of Platelet-Activating Factor (PAF)
Preparation of Highly Potent and Selective Non-Peptide Antagonists of the Arginine Vasopressin V_ Receptor by Introduction of a 2-Ethyl-1H-1-imidazolyl Group
Novel Potassium Channel Activators : Synthesis and Structure-Activity Relationship Studies of 3,4-Dihydro-2H-1,4-benzoxazine Derivatives
Novel Potassium Chennel Activators. II. Synthesis and Pharmacological Evaluation of 3,4-Dihydro-2H-1,4-benzoxazine Derivatives : Modificaiton of the Aromatic Part
Nonpeptide Arginine Vasopressin Antagonists for Both V_ and V_2 Receptors : Synthesis and Pharmacological Properties of 4'-(1,4,5,6-Tetrahydroimidazo[4,5-d][1]benzoazepine-6-carbonyl)benzanilide Derivatives and 4'-(5,6-Dihydro-4H-thiazolo[5,4-d][1]ben
Nonpeptide Arginine Vasopressin Antagonists for Both V_ and V_2 Receptors : Synthesis and Pharmacological Properties of 2-Phenyl-4'-(2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-1-carbonyl)benzanilide Derivatives
Stereoselective Synthesis of Methyl (Z)-(4,4-Difluoro-2,3,4,5-tetrahydro-1H-1-benzazepin-5-ylidene) acetate Using a Dianion Horner-Wadsworth-Emmons Reagent
Preparation of Non-peptide, Highly Potent and Selective Antagonists of Arginine Vasopressin V_ Receptor by Introduction of Alkoxy Groups
Highly Potent and Orally Active Non-Peptide Arginine Vasopressin Antagonists for Both V_ and V_2 Receptors : Synthesis and Pharmacological Properties of 4'-[(4,4-Difluoro-5-methylidene-2,3,4,5-tetrahydro-1H-1-benzoazepin-1-yl)carbonyl]-2-phenylbenzani
Nonpeptide Arginine Vasopressin Antagonists for Both V_ and V_2 Receptors : Synthesis and Pharmacological Properties of 2-Phenyl-4'-[(2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]benzanilide Derivatives
Nonpeptide Arginine Vasopressin Antagonists for Both V_ and V_2 Receptors : Synthesis and Pharmacological Properties of 4'-[5-(Substituted Methylidene)-2,3,4,5-tetrahydro-1H-1-benzoazepine-1-carbonyl]benzanilide and 4'-[5-(Substituted Methyl)-2,3-dihy
Broad spectrum and potent antitumor activities of YM155, a novel small-molecule survivin suppressant, in a wide variety of human cancer cell lines and xenograft models

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