Kaku Tohru | Department Of Human Biology And Pathophysiology School Of Dentistry Health Sciences University Of Ho
スポンサーリンク
概要
- KAKU Tohruの詳細を見る
- 同名の論文著者
- Department Of Human Biology And Pathophysiology School Of Dentistry Health Sciences University Of Hoの論文著者
関連著者
-
KAKU Tohru
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
Kawakami Toshiyuki
Department Of Oral Health Science Graduate School Of Dental Medicine Hokkaido University
-
Kaku T
Department Of Oral Pathology School Of Dentistry Health Sciences University Of Hokkaido
-
ABIKO Yoshihiro
Department of Dental Science, Institute of Personalized Medical Science, Health Sciences University
-
NISHIMURA Michiko
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
Sato Masaaki
Department Of Dental Science Institute Of Personalized Medical Science Health Sciences University Of
-
Saitoh Masato
Department Of Dental Science Institute Of Personalized Medical Science Health Sciences University Of
-
SAITOH Masato
Department of Dental Science, Institute of Personalized Medical Science, Health Sciences University
-
YAMAZAKI Mami
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
OHUCHI Tomoyuki
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
Arai Jiro
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
Takata Takashi
Department Of Oral Biochemistry School Of Dentistry Health Sciences University Of Hokkaido
-
Kusano K
First Department Of Oral And Maxillofacial Surgery School Of Dentistry Health Sciences University Of
-
Kusano Kaoru
北海道医療大学 歯学部口腔外科学第1
-
Yamazaki Mami
Department Of Oral Pathology School Of Dentistry Health Sciences University Of Hokkaido
-
Yamazaki Mami
Department Of Molecular Biology And Biotechnology Graduate School Of Pharmaceutical Sciences Chiba U
-
Takuma Taishin
Department Of Oral Biochemistry School Of Dentistry Health Sciences University Of Hokkaido
-
Shimono Masaki
Pathology Tokyo Dental College
-
Saitoh M
Department Of Dental Science Institute Of Personalized Medical Science Health Sciences University Of
-
KUSANO Kaoru
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
Muramatsu T
Department Of Frontier Surgery Graduate School Of Medicine Chiba University
-
TAKESHIMA Maiko
Department of Pediatric Dentistry, School of Dentistry, Health Sciences University of Hokkaido
-
ARAKAWA Toshiya
Department of Oral Biochemistry, School of Dentistry, Health Sciences University of Hokkaido
-
TAKUMA Taishin
Department of Oral Biochemistry, School of Dentistry, Health Sciences University of Hokkaido
-
Nakade Osamu
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
Muramatsu Takashi
Department Of Developmental Medicine (pediatrics) Osaka University Graduate School Of Medicine
-
Muramatsu Takashi
Department Of Pediatric Dentistry School Of Dentistry Health Sciences University Of Hokkaido
-
Muramatsu Takashi
Department Of Biochemistry Nagoya University School Of Medicine
-
Tsutsumi M
Department Of Oncological Pathology Cancer Center Nara Medical University
-
Tsutsumi Masahiro
Department Of Pathology Saiseikai Chuwa Hospital
-
Kuboki Yoshinori
Dept Biochem Sch Dentistry Hokkaido University
-
Nakade Osamu
Deparment Of Oral Pathology School Of Dentistry Health Sciences University Of Hokkaido
-
INOUE Takashi
Department of Neurosurgery, School of Medicine, Iwate Medical University
-
KURASHIGE Yoshihito
Department of Pediatric Dentistry, School of Dentistry, Health Sciences University of Hokkaido
-
INOUE Takashi
Oral Health Science Center, Tokyo Dental College
-
NASHIMOTO MASANORI
Department of Pathology, Tokyo Dental College
-
Shibata Toshiyuki
Department Of Oral Surgery Graduate School Of Medicine Gifu University
-
Kaku Tohru
Department Of Oral Pathology Hokkaido Health Sciences University Of Hokkaido
-
Kuboki Y
Hokkaido University
-
Kuboki Yoshinori
Emeritus Professor Hokkaido University
-
Majima Toshimitsu
Department Of Oncological Pathology Cancer Center
-
Kuboki Yoshinori
Dept. Of Oral Health Science Graduate School Of Dental Medicine Hokkaido University
-
SHIBATA Toshiyuki
Department of Oral and Maxillofacial Surgery, Gifu University School of Medicine
-
NAKAMURA Sumiko
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
MIZOGUCHI Itaru
Department of Orthodontics, School of Dentistry, Health Sciences University of Hokkaido
-
ITO Yumi
Department of Oral Pathology, Kanagawa Dental College
-
ARISUE Makoto
Department of Oral Maxillo-facial Surgery, School of Dentistry, Health Sciences University of Hokkai
-
Mitamura Jiro
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
KURAGUCHI Jun
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
Ariji Hirohiko
Department of Oral Pathology, Health Sciences University of Hokkaido
-
Ikeda Tatsuru
Department of Clinical Pathology, School of Medicine, Sapporo Medical University
-
Rahemtulla Firoz
Department Of Oral Biology University Of Alabama At Birmingham
-
Saitoh Masato
Dep. Of Dental Sci. Inst. Of Personalized Medical Sci. Health Sciences Univ. Of Hokkaido
-
Nakamura Sumiko
Department Of Oral Pathology School Of Dentistry Health Sciences University Of Hokkaido
-
Ito Yumi
Department Of Oral Pathology Kanagawa Dental College
-
Ito Yumi
Department Of Cell Biology Institute Of Nephrology Faculty Of Medicine Niigata University:division O
-
Inoue T
Department Of Pathophysiology Tokyo Dental College
-
Sakakura Yasunori
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido
-
Koyama Hideki
Deparment Of Oral Pathology School Of Dentistry Health Sciences University Of Hokkaido
-
Takita Hiroko
Department Of Oral Health Science Graduate School Of Dental Medicine Hokkaido University
-
Takita H
Central Research Institute
-
Kaku Tohru
School Of Dentistry Health Sciences University Of Hokkaido
-
Ikeda T
北海道医療大学 歯 口腔病理
-
Ikeda T
Sapporo Medical Univ. School Of Medicine Hokkaido Jpn
-
Ikeda Tatsuru
Department Of Clinical Pathology Sapporo Medical University School Of Medicine
-
Arisue Makoto
Department Of Oral And Maxillofacial Surgery School Of Dentistry Health Sciences University Of Hokka
-
Mitamura Jiro
Department Of Oral Pathology School Of Dentistry Health Sciences University Of Hokkaido
-
Kuraguchi Jun
Department Of Oral Pathology Health Sciences University Of Hokkaido
-
Ariji Hirohiko
Deparment Of Oral Pathology School Of Dentistry Health Sciences University Of Hokkaido
-
Fukumoto Yoshihiro
Department Of Cardiovascular Medicine Tohoku University Graduate School Of Medicine
-
TANAKA Hiroshi
Department of Pediatrics, Hirosaki University School of Medicine
-
AOKI Takashi
Department of Molecular Biosciences, School of Pharmaceutical Sciences, Health Sciences University o
-
KOYAMA Hiroki
Department of Breast Surgery, Osaka Medical Center
-
HANIFFA Abusayeed
Office of Deputy Provincial Director of Health Services
-
NAGAYASU Hiroki
Department of Dental Science, Division of Oral Medicine & Pathology, Institute of Personalized Medic
-
SUGIURA Chihiro
Department of Oral Surgery, University of Hokkaido
-
MUTHUMALA Malantha
General Hospital Kalutara
-
CHIBA Itsuo
Department of Preventive and Community Dentistry, School of Dentistry, Health Sciences University of
-
NORO Daisuke
Department of Dental Science, Institute of Personalized Medical Science, Health Sciences University
-
IGARASHI Seiji
Department of Pediatric Dentistry, School of Dentistry, Health Sciences University of Hokkaido
-
NAKASHIMA Keisuke
Department of Periodontology, Health Sciences University of Hokkaido
-
OGAWA Ikuko
Centre of Oral Clinical Examination, Hiroshima University Hospital
-
HATTORI Yufo
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
ABE Uichi
Department of Oral Surgery, School of Medicine, Gifu University
-
MATSUDA Shinji
Department of Pathology, Kouseiren Takaoka Hospital
-
TAKATA Takashi
Centre of Oral Clinical Examination, Hiroshima University Hospital
-
Yamaguchi Masaru
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
JINBU Yoshinori
Department of Dentistry and Oral Surgery, Jich Medical School
-
NOGUCHI Tadahide
Department of Dentistry and Oral Surgery, Jich Medical School
-
MURATA Masaru
Department of Oral Maxillo-facial Surgery, School of Dentistry, Health Sciences University of Hokkai
-
TAIRA Toshio
Hokkaido Laboratories, Sangi Co. Ltd.,
-
SHIMONO Masaki
Department of Pathology, Tokyo Dental College
-
KUBOKI Yoshinori
Oral Health Science, Graduate School of Dental Medicine, Hokkaido University
-
SATOH Masaaki
Department of Clinical Pathology, School of Medicine, Sapporo Medical University
-
Koyama Hideki
Department of Oral Pathology, Health Sciences University of Hokkaido
-
Iwaki Hiroyuki
Department of Clinical Pathology, School of Medicine, Sapporo Medical University
-
Narimatsu Eimei
Department of Clinical Pathology, School of Medicine, Sapporo Medical University
-
Sekiguchi Takashi
Department of Oral and Maxillofacial Surgery, School of Medicine, Sapporo Medical University
-
Kohama Gen-iku
Department of Oral and Maxillofacial Surgery, School of Medicine, Sapporo Medical University
-
SEIKI Motoharu
Department of Cancer Cell Research, Institute of Medical Science, University of Tokyo
-
Kubo Toshihiko
Department of Cardiology, Matsuyama Red-Cross Hospital
-
Abe Uichi
Department Of Oral Surgery School Of Medicine Gifu University
-
Chiba Itsuo
Department Of Preventive And Community Dentistry School Of Dentistry Health Sciences University Of H
-
Hattori Yufo
Department Of Oral Pathology School Of Dentistry Health Sciences University Of Hokkaido
-
Murata Masaru
北海道医療大学 歯 第2口腔外科
-
Koyama Hiroki
Department Of Breast And Endocrine Surgery Osaka Medical Center For Cancer And Cardiovascular Diseas
-
TANAKA YOICHI
Division of Surgical Pathology, Clinical Laboratory, Ichikawa General Hospital, Tokyo Dental College
-
KANNO Hidetoshi
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
Murata M
Okayama Univ. Okayama Jpn
-
Nakashima Keisuke
Department Of Frontier Materials. Nagoya Institute Of Technology
-
Ueda Yasuo
Dept. Of Oral Functional Science Graduate School Of Dental Medicine Hokkaido University
-
Monma Y
Higashi‐nippon‐gakuen Univ. Hokkaido Jpn
-
Monma Yoshio
Department Of Pharmacology School Of Medicine Hokkaido University:(present Address)department Of Pha
-
Sato Masaaki
Department Of Clinical Pathology Sapporo Medical University
-
Seiki Motoharu
Department Of Cancer Cell Research Institute Of Medical Science University Of Tokyo
-
Kubo Toshihiko
The Department Of Cardiovascular Medicine Kitakyushu Municipal Medical Center
-
Shimono Masaki
Department Of Biosphere Science Faculty Of Science Toyama University
-
Satoh Noriyuki
Department of Biology, Niigata University
-
Sadaoka Toshiyuki
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
Ohno Yuju
Internal Medicine Kitakyushu Municipal Medical Center
-
Endo Kazuhiko
Division Of Biomaterials And Bioengineering Department Of Oral Rehabilitation School Of Dentistry He
-
Endo Kazuhiko
Silicon Systems Research Laboratories Nec Corporation
-
Endo Kazuhiko
Department Of Dental Materials Science School Of Dentistry Health Sciences University Of Hokkaido
-
Urabe Yoshitoshi
Departments of Cardiovascular Medicine, Kitakyushu Municipal Medical Center
-
Johkou Takatoshi
Department of Renal Medicine, Moji-Ekisaikai Hospital
-
KUBOKI Yoshinori
Department of Oral Biochemistry, School of Dentistry, Hokkaido University
-
Scott Paul.G.
Department of Biochemistry, Heritage Medical Research Centre
-
Dodd Carole
Department of Biochemistry, Heritage Medical Research Centre
-
Takita Hiroko
Department Of Biochemistry Hokkaido University Dental School
-
Nakashima Keisuke
Department Of Periodontology Health Sciences University Of Hokkaido
-
Yajima T
北海道医療大学 口腔解剖
-
Yajima Toshihiko
Department Of Oral Anatomy Higashi-nippon-gakuen University School Of Dentistry
-
Kaku Tohru
Department Of Oral Pathology School Of Dentistry Health Sciences University Of Hokkaido
-
Kaku Tohru
Departments Of Cardiovascular Medicine Kitakyushu Municipal Medical Center
-
Kaku Tohru
Department Of Oral Pathology School Of Dentistry Higashi-nitipon-gakuen University
-
Kaku Tohru
Department Of Oral Pathology Health Sciences University Of Hokkaido School Of Dentistry
-
Kaku Tohru
Department Of Oral Pathology School Of Dentistry
-
Ohnishi Takashi
Department Of Dental Radiology School Of Dentistry Health Sciences University Of Hokkaido
-
Ogawa Ikuko
Centre Of Oral Clinical Examination Hiroshima University Hospital
-
SUDO Jun-ichi
Department of Pharmacology, Faculty of Medicine, University of Tokyo
-
TAKADA JUNICHI
Department of Orthopedic Surgery, Sapporo Medical University
-
Sato Noriyuki
Dept. Of Oral Health Science Graduate School Of Dental Medicine Hokkaido University
-
Ueda Yasuo
Department Of Oral Functional Science Hokkaido University Graduate School Of Dental Medicine
-
Kuboki Yoshinori
Department Of Biochemistry Hokkaido University School Of Dentistry
-
Urabe Yoshitoshi
The Department Of Cardiovascular Medicine Kitakyushu Municipal Medical Center
-
Urabe Yoshitoshi
Deparment Of Cardiovascular Medicine Kitakyushu Municipal Medical Center
-
Johkou Takatoshi
Department Of Renal Medicine Moji-ekisaikai Hospital
-
Murata Masaru
Department Of Oral Maxillofacial Surgery School Of Dentistry Health Sciences University Of Hokkaido
-
OHNO Hiroki
Department of Dental Materials Science, School of Dentistry, Health Sciences University of Hokkaido,
-
SUZUKI Masahiro
Department of Cardiology, National Hospital Organization Saitama Hospital
-
IRIE KAZUHARU
Department of Oral Anatomy, Health Sciences University of Hokkaido School of Dentistry
-
TSURUGA EICHI
Department of Oral Anatomy, Health Sciences University of Hokkaido School of Dentistry
-
Nagayasu Hiroki
Department Of Dental Science Division Of Oral Medicine & Pathology Institute Of Personalized Med
-
Ohata Noboru
Department of Prosthetic Dentistry II, School of Dentistry, Hokkaido University
-
Matsuda Shinji
Department Of Biology Faculty Of Pharmaceutical Sciences Hoshi University
-
Shiota Hiroyuki
Medical Device Group, Nippon Cable System Inc.
-
Seki Yasuo
Medical Device Group, Nippon Cable System Inc.
-
Ohata Noboru
Department Of Oral Functional Science Hokkaido University Graduate School Of Dental Medicine
-
Takahashi Kanae
Department Of Animal Husbandry Faculty Of Agricultue Tohoku University
-
Takahashi Kanae
Department Of Oral Pathology School Of Dentistry
-
Kubota Takashi
Department of Oral and Maxillofacial Surgery, Mitsubishi Kyoto Hospital
-
KUSANO Kaoru
First Department of Oral and Maxillofacial Surgery, School of Dentistry, Health Sciences University
-
FUJIMOTO Atsushi
Medical Corporation Keijin-kai, Nishimaruyama Hospital, Dental Department
-
LIU Fang
Department of Oral Pathology, School of Dentistry, Health Sciences University of Hokkaido
-
SHI Sizhen
Institute of Pediatric Dentistry, School of Dentistry, Tongji University
-
Yajima Toshihiko
Department Of Dental Radiology School Of Dentistry Health Sciences University Of Hokkaido
-
Tanabe Tsuneyoshi
Dept. Of Toxicol. & Clin. Pharmacol. Fac. Of Pharmaceut. Sci. Higashi-nippon-gakuen Univ.
-
Tanabe Tsuneyoshi
Department Of Toxicology Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
-
Tanabe Tsuneyoshi
Department Of Toxicology And Clinical Pharmacology Faculty Of Pharmaceutical Sciences Higashi-nippon
-
Tanabe Tsuneyoshi
Department Of Pharmacology And Toxitology Faculty Of Pharmaceutical Sciences
-
Komori Kiyoshi
Department Of Cancer Cell Research Institute Of Medical Science University Of Tokyo
-
Takita Hiroko
Central Research Institute
-
Liu Fang
Department Of Analysis Of Traditional Chinese Medicine School Of Traditional Chinese Medicine Shenya
-
Endo Kazuhiko
Department Of Dental Materials Science Health Sciences University Of Hokkaido School Of Dentistry
-
Endo Kazuhiko
Department Of Dental Materials Science School Of Dentistry Health Science University Of Hokkaido
-
Murata Masaru
Department Of Architecture And Building Engineering School Of Engineering
-
Uno Keiji
Dept. Of Oral Functional Science Graduate School Of Dental Medicine Hokkaido University
-
Scott Paul.g.
Department Of Biochemistry Heritage Medical Research Centre
-
Ohata Noboru
Dept. Of Oral Functional Science Graduate School Of Dental Medicine Hokkaido University
-
Vehof Johan
School Of Dentistry University Of Nijmegen Nijmegen The Netherlands University
-
Seki Yasuo
Medical Device Department Hi-lex Corporation
-
Shi Sizhen
Institute Of Pediatric Dentistry School Of Dentistry Tongji University
-
Jansen John
School Of Dentistry University Of Nijmegen Nijmegen The Netherlands University
-
Tanaka Yoichi
Division Of Surgical Pathology Clinical Laboratory Ichikawa General Hospital Tokyo Dental College
-
Dodd Carole
Department Of Biochemistry Heritage Medical Research Centre
-
Ohno Hiroki
北海道医療大学 歯学部歯科矯正学
-
Ohno H
Division Of Biomaterials And Bioengineering Department Of Oral Rehabilitation School Of Dentistry He
-
Ohno Hiroki
Department Of Biology Kyoto University Of Education
-
Nakade Osamu
Department Of Oral Pathology School Of Dentistry
-
Tsuruga Eichi
Department Of Oral Anatomy Health Sciences University Of Hokkaido School Of Dentistry
-
Tsuruga Eichi
Department Of Biochemistry School Of Dentistry Hokkaido University
-
Irie Kazuharu
Department Of Oral Anatomy School Of Dentistry Health Sciences University Of Hokkaido
-
Sudo J
Department Of Clinical Pharmacology And Toxicology Faculty Of Pharmceutical Sciences Health Sciences
-
Sudo Jun-ichi
Department Of Clinical Pharmacology And Toxicology Faculty Of Pharmaceutical Sciences Health Science
-
Kawakami Johji
First Department Of Oral And Maxillofacial Surgery School Of Dentistry Health Sciences University Of
-
Takada Junichi
Department Of Orthopedic Surgery School Of Medicine Sapporo Medical University
-
Muto Toshitaka
First Department Of Oral And Maxillofacial Surgery School Of Dentistry Health Sciences University Of
-
Kohama Gen-iku
Department Of Oral And Maxillofacial Surgery School Of Medicine Sapporo Medical University
-
Tanaka Hiroshi
Department Of Cardiology Jichi Medical School
-
Satoh Noriyuki
Department Of Biology Niigata University
著作論文
- Expression pattern of p63 in oral epithelial lesions and submucous fibrosis associated with betel-quid chewing in Sri Lanka
- Increased expression of β-defensin-2 and -3 during the development of autoimmune sialoadenitis in MRL/Ipr mice
- Effect of defensin peptides on eukaryotic cells : primary epithelial cells, fibroblasts and squamous cell carcinoma cell lines
- Atypical carcinoid (neuroendocrine carcinoma) of the gingiva : Counterpart of a laryngeal tumor
- An Immunohistochemical Study of the Localization of Inducible Nitric Oxide Synthase (iNOS) and Heat Shock Protein (HSP) in Pleomorphic Adenoma
- Localization of human β-defensin 3 mRNA in normal oral epithelium, leukoplakia, and lichen planus : an in situ hybridization study
- Immunohistochemical localization of amelogenin in human odontogenic tumors, using a polyclonal antibody against bovine amelogenin
- Primary Intraosseous Carcinoma : A review of Japanese cases
- Localization of p21/waf-1/cip-1 mRNA at the Terminal Differentiated Stage in Rat Dental Tissues
- BCL-2 expression in epithelial rest of Malassez, both in vivo and in vitro
- Apoptosis in the Reduced Enamel Epithelium just after Tooth Emergence in Rats : In Situ Labeling of Nuclear DNA Fragmentation and Electron Microscopic Studies
- Salivary Duet Carcinoma : Report of a case, immunohistochemical studies and a survey of Japanese cases
- Polymorphous Low Grade Adenocarcinoma of Minor Salivary Gland Origin in the Oral Floor : Report of a case with an immunohistochemical study and an analysis of proliferative activity
- Apoptotic cell death at tooth eruption in rat molar observed by in situ labeling of nuclear DNA fragmentation
- Histological Patterns of Salivary Gland Tumor Observed by Confocal Laser Scanning Microscope
- A Case of Pulmonary Embolism Caused by Paroxysmal Nocturnal Hemoglobinuria
- Immunohistochemical localization of large chondroitin sulfate proteoglycan in odontogenic tumor
- An Immunohistochemical Study of the Localization of Biglycan, Decorin and Large Chondroitin-sulphate Proteoglycan in Pleomorphic Adenoma
- Effects of Extracellular Calcium on the Proliferation, Differentiation and Gene Expressions of Bone Morphogenetic Proteins-2 and -4 in Human Gingiva-Derived Fibroblasts
- Single-nucleotide Polymorphism (SNP) in β-Defensin 2 in a Japanese Population and an Effect of - 1029 SNP on Promoter Activity
- Upregulated expression of human β defensin-1 and-3 mRNA during differentiation of keratinocyte immortalized cell lines, HaCaT and PHK16-Ob
- Expression of inflammatory cytokines and beta-defensin 1 mRNAs in porcine epithelial rests of Malassez in vitro
- Effects of mechanical stress on the eryression of type XII collagen mRNA in human periodontal ligament cells
- Impaired alveolization in mice deficient in membrane-type matrix metalloproteinase 1 (MT1-MMP)
- A case of inverted papilloma of the maxillary sinus
- PROTECTIVE EFFECTS OF ADRENOCEPTOR-BLOCKING AGENTS ON MYOCARDIAL INJURY INDUCED BY EPINEPHRINE IN MICE
- Rationale for hydroxyapatite coating on 3D-titanium web enhancing bone formation(15thAnnual Meeting of the Society for Hard Tissue Regenerative Biology,Session 2)
- Corrosion Resistance and Biocompatibility of High Nitrogen-bearing Stainless Steels
- Effect of extracellular calcium on the gene expression of bone morphogenetic protein-2 and -4 of normal human bone cells
- A Case of a Concrescence
- Clear-Cell Variant of Mucoepidermoid Carcinoma in the Parotid Gland : Case report and immunohistochemical study
- Nicotine induces upregulated expression of beta defensin-2 via the p38MAPK pathway in the HaCaT human keratinocyte cell line