Yokoi T | Laboratory Of Drug Metabolism Graduate School Of Pharmaceutical Sciences Hokkaido University
スポンサーリンク
概要
- 同名の論文著者
- Laboratory Of Drug Metabolism Graduate School Of Pharmaceutical Sciences Hokkaido Universityの論文著者
関連著者
-
Yokoi T
Laboratory Of Drug Metabolism Graduate School Of Pharmaceutical Sciences Hokkaido University
-
Yokoi T
Department Of Medicine And Clinical Science Gunma University Graduate School Of Medicine
-
Yokoi Tsuyoshi
Laboratory Of Drug Metabolism Division Of Pharmacobio-dynamics Graduate School Of Pharmaceutical Sci
-
Yokoi Tsuyoshi
Fac.pharm. Sci. Hokkaido Univ.
-
Tsumita Yuki
Department Of Medicine And Clinical Science Gunma University Graduate School Of Medicine
-
Kamataki Tetsuya
Laboratory Of Drug Metabolism Division Of Pharmacobio-dynamics Graduate School Of Pharmaceutical Sci
-
Yokoi Tsuyoshi
北海道大学 薬研究 代謝分析
-
Kamataki T
Hokkaido Univ. Sapporo Jpn
-
Yokoi Tsuyoshi
Division Of Drug Metabolism And Toxicology Faculty Of Pharmaceutical Sciences Kanazawa University
-
Nakayama Kazuo
Laboratory Of Drug Metabolism Division Of Pharmacobio-dynamics Graduate School Of Pharmaceutical Sci
-
Nakamura Katsunori
Department Of Clinical Pharmacology Graduate School Of Medicine Gunma University
-
Nakayama K
Laboratory Of Drug Metabolism Graduate School Of Pharmaceutical Sciences Hokkaido University
-
Kamataki Tetsuya
Lab.drug Metab. Grad.sch.pharm.sci. Hokkaido Univ.
-
KAMATAKI Tetsuya
Laboratory of Drug Metabolism, Graduate School of Pharmaceutical Sciences, Hokkaido University
-
YOKOI Tsuyoshi
Laboratory of Drug Metabolism, Hokkaido University Graduate School of Pharmaceutical Sciences
-
Kamataki Tetsuya
Laboratory Of Drug Metabolism Graduate School Of Pharmaceutical Sciences Hokkaido University
-
KAMATAKI Tetsuya
Division of Drug Metabolism, Faculty of Pharmaceuti-cal Sciences, Hokkaido University
-
NAKAMURA Katsunori
Department of Clinical Pharmacology, Graduate School of Medicine, Gunma University
-
YOKOI Tsuyoshi
Division of Analytical Biochemistry, Faculty of Pharmaceutical Sciences, Hokkaido University
-
Kamataki Tetsuya
Division Of Analytical Biochemistry Faculty Of Pharmaceutical Sciences Hokkaido University
-
Yokoi Tsuyoshi
Division Of Analytical Biochemistry Faculty Of Pharmaceutical Sciences Hokkaido University:explorato
-
Nakayama Katsuo
Department Of Clinical Pharmacology Graduate School Of Medicine Gunma University
-
Fujita K
Graduate School Of Science Osaka City University
-
Fujita Ken-ichi
Laboratory Of Drug Metabolism Graduate School Of Pharmaceutical Sciences Hokkaido University
-
Fujita Ken-ichi
Lab.drug Metab. Grad.sch.pharm.sci. Hokkaido Univ.
-
Fujita K
Laboratory Of Drug Metabolism Graduate School Of Pharmaceutical Sciences Hokkaido University
-
Kamataki Tetsuya
Department Of Pharmacology School Of Medicine Keio University:department Of Analytical Biochemistry
-
NAKAGAWA Tetsuya
Div.Drug Metabol., Fac.Pharm.Sci., Hokkaido Univ.
-
Kushida Hirotaka
Medicinal Evaluation Laboratory Tsumura & Co.
-
Nakagawa Tetsuya
Div.drug Metabol. Fac.pharm.sci. Hokkaido Univ.
-
Fujieda Masaki
北海道大学 薬学研究院薬物代謝学
-
Fujieda Masaki
Laboratory Of Drug Metabolism Graduate School Of Pharmaceutical Sciences Hokkaido University
-
Fujieda Masaki
北海道大学 薬研究 代謝分析学
-
YAMAMOTO Koujirou
Department of Pharmacy, The University of Tokyo Hospital, Faculty of Medicine, University of Tokyo
-
HORIUCHI RYUYA
Department of Clinical Pharmacology, Gunma University Graduate School of Medicine
-
Horiuchi Ryuya
Department Of Pharmacy The Gunma University Hospital Gunma University School Of Medicine:department
-
FUNAYAMA Masato
Department of Legal Medicine, Sapporo Medical University
-
YOKOI Tsuyoshi
Div.Drug Metab., Fac.of Pharm.Sic., Hokkaido Univ.
-
KATSUKI Motoya
Dept.DNA Biol.Embryo Engn., Inst.Med.Sci., The Univ.of Tokyo
-
Yamamoto Keiko
Department Of Pharmaceutics
-
Nagayama Sekio
Division Of Drug Metabolism Faculty Of Pharmaceutical Sciences Hokkaido University
-
Horiuchi Ryuya
Department Of Clinical Pharmacology Gunma University Graduate School Of Medicine
-
Yamamoto Koujirou
Department Of Pharmacy The University Of Tokyo Hospital Faculty Of Medicine The University Of Tokyo
-
Yamamoto Koujirou
Department Of Pharmacy The Gunma University Hospital Gunma University School Of Medicine:department
-
Yamamoto Koujirou
Department Of Clinical Pharmacology Gunma University School Of Medicine
-
Yamamoto Koujirou
Department Of Clinical Pharmacology Gunma University Graduate School Of Medicine
-
Fujita Ken-ichi
Div Drug Metab. Pharm.sci. Hokkaido Univ.
-
Katsuki Motoya
Center For Experimental Medicine Institute Of Medical Science University Of Tokyo
-
Kinoshita M
Otsuka Pharmaceutical Co. Tokushima
-
Funayama Masato
Department Of Forensic Medicine Tohoku University School Of Medicine
-
Funayama M
Laboratory Of Drug Metabolism Graduate School Of Pharmaceutical Sciences Hokkaido University
-
KAWAGUCHI Yasuro
Biological Research Laboratory, Taiho Pharmaceutical Co., Ltd.
-
Fujieda Masaki
Lab. Of Drug Metabolism And Pharmacokinetics Showa Pharmaceutical Univ.
-
Katsuki Motoya
Dept.dna Biol.embryo Engn. Inst.med.sci. The Univ.of Tokyo
-
Horiuchi Ryuya
Department Of Clinical Pharmacology And Department Of Pharmacy Gunma University School Of Medicine
-
Kawaguchi Yasuro
Biological Research Laboratory Taiho Pharmaceutical Co. Ltd.
-
Tsukamoto Norifumi
Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine
-
Nojima Yoshihisa
Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine
-
Shioyama Y
Kyushu Univ. Fukuoka
-
Shioyama Yoshiyuki
九州大学生体防御医学研究所
-
MUSHIRODA Taisei
Laboratory for Pharmacogenetics, RIKEN SNP Research Center
-
Mushiroda Taisei
Laboratory For Pharmacogenetics Riken Snp Research Center
-
Mushiroda Taisei
北海道大学 薬研究 代謝分析
-
Mushiroda Taisei
Laboratory Of Drug Metabolism Division Of Pharmacobio-dynamics Graduate School Of Pharmaceutical Sci
-
YOKOTA Jun
Biology Division, National Cancer Center Research Institute
-
Gonzalez Frank
Lab. Mol. Carcinogen.
-
Tsukamoto Norifumi
Department Of Medicine And Clinical Science Graduate School Of Medicine
-
Tsukamoto Norifumi
群馬大学 医学系研究科生体統制内科学
-
Tsukamoto Norifumi
Kidney・rheumatic Medicine
-
Tsukamoto Norifumi
Department Of Medicine And Clinical Science
-
中島 美紀
金沢大学 大学院医学系研究科薬物代謝化学
-
中島 美紀
金沢大学薬学部薬物代謝化学教室
-
Nakajima Miki
Laboratory Of Drug Metabolism Graduate School Of Pharmaceutical Sciences Hokkaido University
-
TERADA Tomoyuki
Laboratory of Biochemistry, Faculty of Pharmacy, Osaka Ohtani University
-
Ishizaki Takashi
Department of Pharmacology and Therapeutics, Graduate School of Clinical Pharmacy, Kumamoto Universi
-
NOHMI Takehiko
Natl. Inst. Health Sci.
-
TANAKA Hirotoshi
Department of Psychosomatic Medicine, Faculty of Medicine, Kyushu University
-
FUJITA Ken-ichi
Division of Drug Metabolism and Molecular Toxicology, Faculty of Pharmaceutical Sciences, Tohoku Uni
-
Ueki Kazue
Department of Internal Medicine, Toho Hospital
-
Okada Yuko
Department Of Clinical Pharmacology Graduate School Of Medicine Gunma University
-
Hara A
Department Of Applied Biological Chemistry Faculty Of Agriculture Meijo University
-
Kubota Megumi
Laboratory Of Drug Metabolism Division Of Pharmacobio-dynamics Graduate School Of Pharmaceutical Sci
-
GONZALEZ Frank
Natl. Cancer Inst., Natl. Inst. Health
-
SHIRAISHI Hiroaki
Laboratory of Biochemistry, Gifu Pharmaceutical University
-
KODAMA Tomoko
Department of Policy Sciences, National Institute of Public Health
-
NAKAMURA Katsunori
Laboratory of Drug Metabolism, Hokkaido University Graduate School of Pharmaceutical Sciences
-
ARIYOSHI Noritaka
Laboratory of Drug Metabolism, Hokkaido University Graduate School of Pharmaceutical Sciences
-
IWATSUBO Takafumi
Yamanouchi Pharmaceutical Co., Ltd., Drug Metabolism Laboratories
-
FUKUNAGA Yasuhisa
Yamanouchi Pharmaceutical Co., Ltd., Drug Metabolism Laboratories
-
HIGUCHI Saburou
Yamanouchi Pharmaceutical Co., Ltd., Drug Metabolism Laboratories
-
ITOH Kunio
Daiichi Pure Chemicals Co., Ltd., Tokai Research Laboratories
-
SHIMADA Noriaki
Daiichi Pure Chemicals Co., Ltd., Tokai Research Laboratories
-
NAGASHIMA Kazuo
Molecular and Cellular Pathology, Hokkaido University Graduate School of Medicine
-
NAKAMOTO Yoko
Laboratory of Drug Metabolism, Division of Pharmacobio-dynamics, Graduate School of Pharmaceutical S
-
NAKAYAMA Kazuo
Laboratory of Drug Metabolism, Division of Pharmacobio-dynamics, Graduate School of Pharmaceutical S
-
UJJIN Pailin
Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University
-
SATARUG Soisungwan
National Research Center for Environmental Toxicology, University of Queensland
-
NAKAYAMA Kazuo
Div.Drug Metab., Fac.of Pharm.Sic., Hokkaido Univ.
-
LI Yong
Div.Drug Metab., Fac.of Pharm.Sic., Hokkaido Univ.
-
KITAMURA Ryuji
Div.Drug Metab., Fac.of Pharm.Sic., Hokkaido Univ.
-
SASAKI Makoto
Div.Drug Metab., Fac.of Pharm.Sic., Hokkaido Univ.
-
KAMATAKI Tetsuya
Div.Drug Metab., Fac.of Pharm.Sic., Hokkaido Univ.
-
ITOH Susumu
Division of Drug Metabolism, Faculty of Pharmaceuti-cal Sciences, Hokkaido University
-
GONDO Yoichi
RIKEN Genomic Sciences Center
-
MUTO Shigeharu
Fac.Pharm., Sci., Hokkaido Univ.
-
YOKOI Tsuyoshi
Fac.Pharm., Sci., Hokkaido Univ.
-
FUJITA Kenichi
Fac.Pharm., Sci., Hokkaido Univ.
-
SHIOYAMA Yoshiyuki
Dept.Radio., Kyushu Univ.
-
GONDO Yoichi
Inst.Med.Sci., Tokai.Univ.
-
KATSUKI Motoya
Inst.Med.Sci., Tokyo Univ.
-
KAMATAKI Tetsuya
Fac.Pharm., Sci., Hokkaido Univ.
-
Fukui Takafumi
Otsuka Assay Laboratories Otsuka Pharmaceutical Co
-
NAKAGAWA Tetsuya
Fac. Phrm. Sci., Hokkaido Univ.
-
YOKOI Tsuyoshi
Fac. Phrm. Sci., Hokkaido Univ.
-
KUSHIDA Hirotaka
Fac. Phrm. Sci., Hokkaido Univ.
-
FUJITA Ken-ichi
Fac. Phrm. Sci., Hokkaido Univ.
-
KAMATAKI Tetsuya
Fac. Phrm. Sci., Hokkaido Univ.
-
中島 美紀
金沢大学大学院医学系研究科:金沢大学大学院薬学部
-
中島 美紀
金沢大学大学院医学系研究科
-
Kitamura Ryuji
Div.drug Metab. Fac.of Pharm.sic. Hokkaido Univ.
-
SATARUG Soisungwan
Laboratory of Drug Metabolism, Graduate School of Pharmaceutical Sciences, Hokkaido University
-
MIZUTANI Mayumi
Laboratory of Drug Metabolism, Graduate School of Pharmaceutical Sciences, Hokkaido University
-
KINOSHITA Moritishi
Otsuka Assay Laboratories, Otsuka Pharmaceutical Co.
-
SAWADA Minoru
Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Hokkaido University
-
ISHIDA Ryoji
Div.Drug Metabol., Fac.Pharm.Sci., Hokkaido Univ.
-
Frank J.GONZALEZ
Lab.Chemothe Aichi Cancer Center Res.Insti., Japan
-
KAMATAKI Tetsuya
Lab.Mol.Carcinogen
-
FUJITA Ken-ichi
Div, Drug Metab., Pharm.Sci., Hokkaido Univ.
-
KUSHIDA Hirotaka
Div, Drug Metab., Pharm.Sci., Hokkaido Univ.
-
SAKUMA Tsutomu
Div, Drug Metab., Pharm.Sci., Hokkaido Univ.
-
NUNOYA Ken-ichi
Div, Drug Metab., Pharm.Sci., Hokkaido Univ.
-
YOKOI Tsuyoshi
Div, Drug Metab., Pharm.Sci., Hokkaido Univ.
-
ENDOU Tsutomu
Central Res.Lab., Tsumura & Co.,
-
KAMATAKI Tetsuya
Div, Drug Metab., Pharm.Sci., Hokkaido Univ.
-
YAMAYOSHI Yasuko
Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Hokkaido University
-
NAKAMURA Katsunori
Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Hokkaido University
-
KUSHIDA Hirotaka
Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Hokkaido University
-
MITSUHASHI Harumi
Rhone-Poulenc Rorer Japan Inc.
-
UENO Takeshi
Rhone-Poulenc Rorer Japan Inc.
-
Hashimoto Hisashi
Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Hokkaido Univ.
-
Nakagawa Tetsuya
Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Hokkaido Univ.
-
CHIDA Michihiro
Laboratory of Drug Metabolism, Division of Pharmacobio-dynamics, Graduate School of Pharmaceutical S
-
KINOSHITA Moritoshi
Otsuka Assay Laboratories, Otsuka Pharmaceutical Co
-
NUNOYA Ken-ichi
Laboratory of Drug Metabolism, Graduate School of Pharmaceutical Sciences, Hokkaido University
-
TAKAHASHI Yuki
Laboratory of Drug Metabolism, Graduate School of Pharmaceutical Sciences, Hokkaido University
-
KIMURA Kanzo
Clincal Research and Development Division, Sumitomo Pharmaceuticals Co., Ltd.
-
KINOSHITA Moritoshi
Diagnostics Division, Otsuka Pharmaceutical Co., Ltd.
-
Frank J.gonzalez
Lab.chemothe Aichi Cancer Center Res.insti. Japan
-
TSUKADA Yoshito
Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine
-
MAEZAWA Akira
Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine
-
ITOH Shinji
Hokkaido College of Pharmacy
-
Terada Tomoyuki
Laboratory Of Biochemistry And Molecular Biology Graduate School Of Pharmaceutical Sciences Osaka Un
-
Nojima Yoshihisa
Department Of Medicine And Clinical Science Graduate School Of Medicine
-
Hashimoto Hisashi
Division Of Applied Biosciences Graduate School Of Agriculture Kyoto University
-
Fujita Ken-ichi
Division Of Drug Metabolism And Molecular Toxicology Faculty Of Pharmaceutical Sciences Tohoku Unive
-
Hara Akira
Department Of Pathology Gifu University School Of Medicine
-
Itoh Susumu
Division Of Drug Metabolism Faculty Of Pharmaceutical Sciences Hokkaido University
-
Sakuma Tsutomu
Div Drug Metab. Pharm.sci. Hokkaido Univ.
-
Ueki Kazue
Department Of Medicine And Clinical Science Gunma University Graduate School Of Medicine
-
Ueki K
Department Of Medicine And Clinical Science Gunma University Graduate School Of Medicine
-
Itoh Kunio
北海道大学 薬 代謝分析
-
Sawada Minoru
Central Research Laboratories Zeria Pharmaceutical Co. Ltd.
-
Kimura Kanzo
Clincal Research And Development Division Sumitomo Pharmaceuticals Co. Ltd.
-
Ujjin Pailin
Department Of Laboratory Medicine Faculty Of Medicine Chulalongkorn University
-
Ishida Ryoji
Div.drug Metabol. Fac.pharm.sci. Hokkaido Univ.
-
Maezawa Akira
Third Department Of Internal Medicine Gunma University School Of Medicine
-
Endou Tsutomu
Central Res.lab. Tsumura & Co.
-
Sawada Minoru
Division Of Drug Metabolism Faculty Of Pharmaceutical Sciences Hokkaido University
-
Nakamoto Yoko
Laboratory Of Drug Metabolism Division Of Pharmacobio-dynamics Graduate School Of Pharmaceutical Sci
-
Kodama Tomoko
Department Of Pharmacy Gunma University Hospital
-
Muto Shigeharu
Fac.pharm. Sci. Hokkaido Univ.
-
Nohmi Takehiko
Natl.inst.health Sci.
-
Nakajima Yasuyo
Department Of Medicine And Molecular Science Gunma University Graduate School Of Medicine
-
Shiraishi Hiroaki
Laboratory Of Biochemistry Gifu Pharmaceutical University
-
Kinoshita Moritoshi
Diagnostic Research Institute Otsuka Pharmaceutical Co. Ltd.
-
Kinoshita Moritoshi
Otsuka Assay Laboratories Gene Analysis Center Life Science Initiative Otsuka Pharmaceutical Co. Ltd
-
Shiraishi Hiroaki
Endocrine Disrupters Research Laboratory National Institute For Environmental Studies
-
Nojima Yoshihisa
The Third Department Of Internal Medicine Gunma University School Of Medicine
-
Nakazato Yoichi
Department Of Medicine And Molecular Science Gunma University Graduate School Of Medicine
-
Higuchi Saburou
Yamanouchi Pharmaceutical Co. Ltd. Drug Metabolism Laboratories
-
Ariyoshi Noritaka
Laboratory Of Drug Metabolism Division Of Pharmacobiodynamics Graduate School Of Pharmaceutical Scie
-
SHIRASAKA Tomonobu
Ishibashi Hospital
-
Ishizaki Takashi
Department Of Clinical Pharmacology Research Institute International Medical Center Of Japan
-
Satarug Soisungwan
Laboratory Of Drug Metabolism Graduate School Of Pharmaceutical Sciences Hokkaido University
-
Satarug Soisungwan
National Res Centre Environl Toxicol
-
Yokota Jun
Biology Division National Cancer Center Research Institute
-
Katsuki Motoya
Inst. Of Med. Sci. Univ. Of Tokyo
-
Shimada Noriaki
Daiichi Pure Chemicals Co. Ltd.
-
Shimada Noriaki
Daiichi Pure Chemicals Co. Ltd. Tokai Research Laboratories
-
Itoh S
Hokkaido College Of Pharmacy
-
Ueki Kazue
Department Of Internal Medicine Toho Hospital
-
Yamayoshi Yasuko
Division Of Drug Metabolism Faculty Of Pharmaceutical Sciences Hokkaido University
-
Tsukada Yoshito
Department Of Medicine And Clinical Science Gunma University Graduate School Of Medicine
-
Kamataki Tetsuya
Dev.drug Metab. Faculty Of Pharm.sic. Hokkaido Univ.
-
Terada Tomoyuki
Laboratory Of Biochemistry And Molecular Biology Graduate School Of Pharmaceutical Sciences Osaka Un
-
Ishizaki Takashi
Department Of Clinical Pharmacology & Therapeutics Hamamatsu University School Of Medicine
-
Itoh Susumu
Division Of Cellular Physiology Faculty Of Pharmaceutical Sciences Osaka University
-
Fujita Kenichi
Fac.pharm. Sci. Hokkaido Univ.
-
Hashimoto Hisashi
Division Of Drug Metabolism Faculty Of Pharmaceutical Sciences Hokkaido Univ.
-
Chida Michihiro
Laboratory Of Drug Metabolism Division Of Pharmacobio-dynamics Graduate School Of Pharmaceutical Sci
著作論文
- A Mutation in the Flavin-containing Monooxygenase 3 Gene and its Effects on Catalytic Activity for N-oxidation of Trimethylamine In Vitro
- Inhibitory Effects of Nicardipine to Cytochrome P450 (CYP) in Human Liver Microsomes(Biopharmacy)
- Co-operative Regulation of the Transcription of Human Dihydrodiol Dehydrogenase(DD)4/Aldo-Keot Reductase(AKR)1C4 Gene by Hepatocyte Nuclear Factor(HNF)-4α/γand HNF-1α.
- Characterization of a Novel Variant (S145C/L311V) of 3α-Hydroxysteroid/Dihydrodiol Dehydrogenase in Human Liver.
- CHARACTERIZATION OF TRANSGENIC MICE CARRYING A HUMAN FETUS-SPECIFIC CYP3A7.
- Inhibiton by EGCG of benzo[a]pyrene-induced mutations in the lung of HITEC mice.
- 2B-08 Establishment of Genetically Engineered E.coli Highly Sensitive to Nitrosamines by Introducing Human CYP2E1
- Genetic Polymorphism in the 5'-Flanking Region of Human CYP1A2 Gene : Effect on the CYP1A2 Inducibility in Humans
- Metabolic Activation of Dimethylnitrosamine(DMN) by Human CYP2E1 Expressed in O^6-Methylguanine-DNA Methyltransferase-Deficient Cells
- EXPRESSION OF RECOMBINANT HUMAN CYTOCHROME P450 (P450 OR CYP) 2A6 IN ESCHERICHIA COLI.
- "S2-3 STRATEGIC PROPOSALS TO AVOID TOXIC DRUG INTERACTIONS DURING NEW DRUG DEVELOPMENT : MOLECULAR TOXICOLOGY PROPOSALS (Strategy how we can learn drug-drug interaction during the development of a new drug)
- Stable expression of CYP3A4 and CYP3A7, adult and fetal-specific forms of cytochrome P450 in human liver, in CHL cells and its application to toxicological testing.
- Detection of Three Genetic Polymorphisms in the 5'-Flanking Region and Intron 1 of Human CYP1A2 in the Japanese Population
- Homologous Unequal Cross-Over within the Human CYP2A Gene Cluster as a Mechanism for the Deletion of the Entire CYP2A6 Gene Associated with the Poor Metabolizer Phenotype
- Thiopurine Methyltransferase Genotype and Phenotype Status in Japanese Patients with Systemic Lupus Erythematosus(Biopharmacy)
- OCCURRENCE OF AUTOANTIBODY TO PROTEIN DISULFIDE ISOMERASE IN PATIENTS WITH HEPATIC DISORDER
- OCCURRENCE OF AUTOANTIBODY TO PROTEIN DISULFIDE ISOMERASE IN RATS WITH XENOBIOTIC-INDUCED HEPATITIS
- Metabolism of MPTP and accumulation of an active metabolite, MPP^+, in the brain of SUNCUS murinus