Saruta T | Department Of Internal Medicine School Of Medicine Keio University
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概要
関連著者
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Takishita S
University Of The Ryukyus
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Sata Masataka
Department of Internal Medicine and Molecular Science, Graduate School of Medicine, Osaka University
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Yamada Hirotsugu
Department Of Cardiovascular Medicine The University Of Tokushima
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荻原 俊男
Division Of Preventive Cardiology National Cardiovascular Center
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Hirata Yasunobu
Cardiovascular Medicine University Of Tokyo
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NAKAO Kazuwa
Kyoto University
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SARUTA Takao
Keio University
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OBA Koji
EBM Research Center, Kyoto University Graduate School of Medicine
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UESHIMA Kenji
EBM Research Center, Kyoto University Graduate School of Medicine
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YASUNO Shinji
EBM Research Center, Kyoto University Graduate School of Medicine
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Saito Yoshihiko
熊本大学 医学教育部循環器病態学
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Saitou Yoshihiko
奈良県立医科大学 総合医療学
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Matsuoka Hiroaki
大阪大学 医学系研究科老年・腎臓内科学
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林田 孝平
国立循環器病センター放射線診療部
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荻原 俊男
大阪大学医学部・老年・腎臓内科
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OGIHARA Toshio
Osaka University
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Muratani H
Department Of Clinical Pharmacology And Therapeutics Tohoku University
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Itoh Hiroaki
Osaka City University
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Itoh Hiroshi
Division 1 Department Of Pathology Kobe University School Of Medicine
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Ohama Tohru
大阪大学 医学系研究科循環器内科学
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Ogihara Toshio
京都大学ebm研究センター
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Kai Hisashi
Department Of Internal Medicine Division Of Cardio-vascular Medicine Kurume University School Of Med
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北 徹
Department Of Geriatric Medicine Osaka University Graduate School Of Medicine
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ISEKI Kunitoshi
University of the Ryukyus
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Kitamura K
Department Of Geriatric Medicine Ehime University Graduate School Of Medicine
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FUJIMOTO Akira
EBM Research Center, Kyoto University Graduate School of Medicine
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Itoh Hiroshi
First Pathology Faculty Of Medical Sciences University Of Fukui
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Itoh Hiroshi
Division Of Surgical Pathology Department Of Biomedical Informatics Kobe University Graduate School
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Itoh Hiroshi
宮崎大学 医学部病理学第2
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KIMURA Kenjiro
St. Marianna University School of Medicine
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Katsuya Tomohiro
東北大学 臨床薬学
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Iseki Kunitoshi
琉球大学 医学研究科臨床薬理学
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Iseki Kunitoshi
琉球大学医学部附属病院 血液浄化療法部
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北 徹
京都大学大学院医学研究科循環器内科学
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KAWANO Yuhei
National Cardiovascular Center
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KATSUYA Tomohiro
Osaka University
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Hoshikawa Yoshiko
Div. Of Molecular And Genetic Medicine Dep. Of Genetic Medicine And Regenerative Therapeutics Gradua
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Kikuchi Kenjiro
Second Department Of Internal Medicine Sapporo Medical College
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Ishii Masao
Japan Medical Association
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Kita Toru
京都大学 医学研究科循環器内科学
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SARUTA Takao
Department of Internal Medicine, School of Medicine, Keio University
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喜多 義邦
Division Of Preventive Cardiology National Cardiovascular Center
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Yamada Hiroyuki
Ami-kyoto Multi-center Risk Study Group
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Makino H
Department Of Medicine And Clinical Science Okayama University Graduate School Of Medicine And Denti
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Makino Hirofumi
大阪大学 医学系研究科老年・腎臓内科学
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北 徹
京都大学老年科
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ITO Masaaki
Mie University
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OHYA Yusuke
University of the Ryukyus
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NAKAO Kazuwa
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
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NAKAO Kazuwa
EBM Research Center, Kyoto University Graduate School of Medicine
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Kamide Kei
国立循環器病センター 高血圧腎臓内科
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Takasaki I
Aichi Medical University
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Kotani Yasushi
国立循環器病センター 予防検診
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Koito Hitoshi
The Cardiovascular Center Kansai Medical University
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Iizuka Masahiko
Department Of Radiology Faculty Of Medicine University Of Tokyo
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Ishii Masao
Department Of Geriatric Medicine Osaka University Graduate School Of Medicine
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Kawano Yuhei
国立循環器病センター 高血圧腎臓内科
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Hori Masatsugu
大阪大学 医学系研究科循環器内科学
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Matsuda Hikaru
Cardiovascular Division Osaka Polici Hospital
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Tomino Y
Department Of Basic Medical Research And Education Ehime University Graduate School Of Medicine
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HIGAKI Jitsuo
Ehime University
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UMEMURA Satoshi
Yokohama City University
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HAYASHI Koichi
Keio University
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HIRAWA Nobuhito
Yokohama City University
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HORIO Takeshi
National Cardiovascular Center
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TSUBAKIHARA Yoshiharu
Osaka General Medical Center
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FUKIYAMA Koshiro
University of the Ryukyus
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HIRAWA Nobuhito
Department of Internal Medicine and Cardiorenal Medicine Yokohama City University Graduate School of
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Umemura S
University Of The Ryukyus
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Umemura Satoshi
熊本大学 医学薬学研究部循環器病態学
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Sasano H
Tohoku University 21st Century Coe Program 'comprehensive Research And Education Center For Pla
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Kita Toru
Department Of Cardiovascular Medicine Kobe City Medical Center General Hospital
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Kita Toru
Department Of Cardiovascular Medicine Graduate School Of Medicine Kyoto University
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Sakamoto Kazuhiko
Division Of Internal Medicine Saito Hospital
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HAYASHI Koichi
Department of Internal Medicine, Keio University School of Medicine
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Tsutsumi Yoshiaki
Genetics Division National Cancer Center Research Institute
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Tsutsumi Yoshiaki
国立循環器病センター
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Harada Takashi
Division Of Nephrology Clinical Research Center National Kyushu Medical Center
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Hayashi Koichi
慶応義塾大学 医学部内科学教室
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Tabara Yasuharu
国立循環器病センター研究所 疫学部
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Tabara Yasuharu
西予市立野村病院 内科
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Shimada Kazuyuki
大阪府立病院機構大阪府立急性期総合医療センター
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Kita Toru
Department Of Geriatric Medicine Graduate School Of Medicine Kyoto University
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Umemura Satoshi
日本大学 医学部内科学系腎臓高血圧内分泌内科
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Umemura Satoshi
横浜市立大学 医学研究科病態制御内科学
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Shirato Kunio
山口大学 医学系研究科器官病態内科学
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Iseki K
University Of The Ryukyus
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Makino Hirofumi
岡山大学 医歯学総合研究科腎・免疫・内分泌代謝内科学
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Makino Hirofumi
Department Of Clinical Gene Therapy Osaka University Graduate School Of Medicine
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Makino Hirofumi
Okayama Univ. Graduate School Of Medicine Dentistry And Pharmaceutical Sci. Okayama Jpn
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Kawano Yuhei
Division Of Hypertension And Nephrology National Cardiovascular Center
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Nagata S
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine
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KURAMOTO Kizuku
Tokyo Metropolitan Geriatric Hospital
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SAITO Yasushi
Chiba University
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TAKASHIMA Seiji
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine
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NAKAI Toshiko
Division of Cardiology, Department of Medicine, Nihon University School of Medicine
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RAKUGI Hiromi
Department of Geriatric Medicine, Osaka University Graduate School of Medicine
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Shimamoto Kazuaki
Sapporo Medical University School of Medicine
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ITOH Hiroshi
Department of Internal Medicine, Keio University School of Medicine
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Yasujima Minoru
Kobe University
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ITO Sadayoshi
Division of Nephrology, Endocrinology and Vascular Medicine, Department of Internal Medicine, Tohoku
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Kato Norihiro
Department of Gene Diagnostic and Therapeutic, Research Institute, International Medical Center of J
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TAMURA Kouichi
Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of
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IMAI Yutaka
Tohoku University
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IMAIZUMI Tsutomu
Kurume University
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ISHIMITSU Toshihiko
Dokkyo Medical University
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ITO Sadayoshi
Tohoku University
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SAITO Ikuo
Keio University
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TSUCHIHASHI Takuya
NHO Kyoto Medical Center
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UESHIMA Hirotsugu
Shiga University of Medical Science
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KIYOHARA Yutaka
Kyushu University
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KOBAYASHI Shotai
Shimane University
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KOHNO Masakazu
Kagawa University
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KUMAGAI Hiroo
National Defense Medical College
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KUSHIRO Toshio
Nihon University
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MINAMI Junichi
Dokkyo Medical University
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MUROHARA Toyoaki
Nagoya University
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TSUTSUI Hiroyuki
Hokkaido University
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UEHARA Yoshio
University of Tokyo
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URA Nobuyuki
Teine Keijinkai Hospital
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WATANABE Tsuyoshi
Fukushima Medical University
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IIMURA Osamu
Sapporo Medical University
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TAKESHITA Akira
Kyushu University
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Nozawa Takashi
Second Department Of Internal Medicine Graduate School Of Medicine University Of Toyama
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KAGAMI Shoji
Department of Pediatrics, School of Medicine, University of Tokushima
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Kohara Katsuhiko
Department Of Cardiovascular Medicine Nephrology And Neurology Faculty Of Medicine And Dialysis Unit
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Mizuta Einosuke
Department of Cardiovascular Medicine, Faculty of Medicine, Tottori University
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Kaikita Koichi
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
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KATSUYA Tomohiro
Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita
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OGIHARA Toshio
Department of Geriatric Medicine, Osaka University Graduate School of Medicine
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MIKI Tetsuro
Department of Geriatric Medicine, Ehime University Graduate School of Medicine
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SHIMADA Kazuyuki
Department of Medicine, Jichi Medical University
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FUKUI Tsuguya
St Luke's International Hospital
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FUKIYAMA Kohshiro
Japan Seaman's Relief Association Moji Hospital
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MORISAKI Takayuki
Department of Biosciences, Research Institute, National Cardiovascular Center
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TAKEDA Kazuo
Kyoto Industrial Health Association
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HIGAKI Jitsuo
Department of Integrated Medicine and Informatics, Ehime University Medical School
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Nonogi Hiroshi
国立循環器病センター研究所 疫学部
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Naritomi Hiroaki
Division Of Cardiology National Cardiovascular Center
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Nakagami Hironori
Division Of Gene Therapy Science Osaka University Graduate School Of Medicine
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Nonogi H
Division Of Cardiology Department Of Internal Medicine National Cardiovascular Center
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SUZUKI Yoshihiko
Suzuki clinic
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Nitta Kosaku
Department of Medicine, Kidney Center, Tokyo Womens Medical University
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SHIRATO Kunio
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
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IGAWA Osamu
Department of Cardiovascular Medicine, Faculty of Medicine, Tottori University
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OHKUBO Takayoshi
Tohoku University 21st Century COE Program 'Comprehensive Research and Education Center for Planning
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Hisatome Ichiro
Division of Regenerative Medicine and Therapeutics, Tottori University Faculty of Medicine
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Sumida Hitoshi
Kumamoto AMI Study Group
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Nara Yasuo
就実大学 薬学部応用薬学
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Fukui Tsuguya
St Luke's International Hospital
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Matsuzaki Masunori
Division Of Cardiology Department Of Medicine And Clinical Science Yamaguchi University Graduate Sch
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Hiro Takafumi
Departments Of Internal Medicine And Cardiology Osaka City University Graduate School Of Medicine
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Yoshida S
Chiba University
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Kangawa Kenji
Department of Biochemistry, National Cardiovascular Center Research Institute
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Nozawa Takashi
富山大学 医学薬学研究部第2内科
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Shimamoto K
Department Of Internal Medicine Ii Sapporo Medical University
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Takata Hiroki
Hokkaido University
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Nonogi Hiroshi
Cardiology And Emergency Medicine National Cardiovascular Center
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Kuwahara Koichiro
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
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Yasuda Yoshinari
National Hospital Organization
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KASHIHARA Naoki
Department of Internal Medicine, Kawasaki Medical School
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Yui Yoshiki
Division Of Cardiorogy Osaka Red Cross Hospital
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伊藤 貞嘉
東北大学病院 腎高血圧内分泌科
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Tobinai K
Hematology And Stem Cell Transplantation Divisions National Cancer Center Hospital
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Tobinai Kensei
国立がんセンター中央病院 血液内科グループ
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橋本 周司
早稲田大学理工学術院 先進理工学研究科
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Kawano Yuhei
Division of Hypertension and Nephrology, National Cardiovascular Center
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Yasuda Hisayo
Division of Hypertension and Nephrology, National Cardiovascular Center
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Miake Junichiro
Division of Immunology, Molecular and Cellular Biology, School of Life Sciences, Tottori University
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Higaki Katsumi
Division of Functional Genomics, Research Center for Bioscience and Technology, Tottori University
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Takagi K
Department Of Medical Technology Nagoya University School Of Health Sciences
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Mochizuki T
Division Of Anti-aging And Genomics Ehime Proteo-medicine Research Center
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Miki Tetsuro
東北大学 臨床薬学
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Mochizuki T
Department Of Radiology Ehime University School Of Medicine Shitsukawa
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Miki Tetsuro
愛媛大学 病態情報内科学
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Yasue H
Kumamoto Univ. School Of Medicine
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Shimada Kazuyuki
山口大学 医学系研究科器官病態内科学
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Saito Y
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine
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Yamashita Shizuya
大阪大学 医学系研究科循環器内科学
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Haketa Akira
Division Of Nephrology Hypertension And Endocrinology Department Of Medicine Nihon University School
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Soma Masayoshi
日本大学 医学部内科学系腎臓高血圧内分泌内科
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Soma Masayoshi
Second Department Of Internal Medicine Nihon University School Of Medicine
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Hara Azusa
Department Of Clinical Pharmacology And Therapeutics Tohoku University
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Kamatani Naoyuki
Laboratory For Statistical Analysis Center For Genomic Medicine Riken
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中山 智祥
Department Of Cardiovascular Renal And Endocrine Medicines Research Center And Cardiovascular Functi
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Kurata Yasutaka
Department Of Cardiovascular Medicine Faculty Of Medicine Tottori University
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Tomoike Hitonobu
National Cardiovascular Center
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Saito Yoshihiko
Department Of Clinical Cell Biology Chiba University Graduate School Of Medicine
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Komamura Kazuo
Department Of Cardiovascular Dynamics Research Institute National Cardiovascular Center
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WATANABE Tsuyoshi
Department of Cell Biology and Neuroscience, Osaka University Graduate School of Medicine
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Ura Nobuyuki
Second Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Ura Nobuyuki
Second Department Of Internal Medicine Sapporo Medical Unversity School Of Medicine
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Ura Nobuyuki
大阪大学 医学系研究科老年腎臓内科学
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Kamitani Shigeki
Saitama Medical University
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Ishimitsu Toshihiko
獨協医科大学 循環器内科
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Ishimitsu Toshihiko
東京大学 第2内科
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Ishimitsu Toshihiko
Department Of Hypertension And Cardiorenal Medicine Dokkyo Medical University
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Miake Junichiro
Dokkyo Medical University
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Minami Junichi
獨協医科大学 循環器内科
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Minami Junichi
Department Of Medicine Division Of Hypertension And Cardiorenal Disease Dokkyo University School Of
著作論文
- A randomized, double-blind, four-arm parallel-group study of the efficacy and safety of azelnidipine and olmesartan medoxomil combination therapy compared with each monotherapy in Japanese patients with essential hypertension : the REZALT study
- Effects of candesartan and amlodipine on cardiovascular events in hypertensive patients with chronic kidney disease : subanalysis of the CASE-J Study
- Effects of Cardiac Complications on Cardiovascular Events in Japanese High-Risk Hypertensive Patients : Subanalysis of the CASE-J Trial
- Relationship between the achieved blood pressure and the incidence of cardiovascular events in Japanese hypertensive patients with complications : a sub-analysis of the CASE-J trial
- Role of diabetes and obesity in outcomes of the candesartan antihypertensive survival evaluation in Japan (CASE-J) trial
- 1 Which Risk Factor Has an Adverse Effect on Coronary Events in Japanese High-risk Hypertensive Patients? : a Subanalysis of CASE-J(Comprehensive Risk Management for Prevention of Coronary Artery Disease,Symposium 16 (SY-16) (H),The 73rd Annual Scientific
- Effect of heart rate on the risk of developing metabolic syndrome
- Decreased body mass index as an independent risk factor for developing chronic kidney disease
- FRS-091 Impairment of Ubiquitin-Proteasome System Caused by a Missense MYBPC3 Mutation and Associated with Cardiac Dysfunction in Hypertrophic Cardiomyopathy(FRS19,Genetic Abnormalities in Cardiac Hypertrophy and Cardiomyopathy (M),Featured Research Sessi
- Association of PLA2G7 polymorphisms with carotid atherosclerosis in hypertensive Japanese
- Impact of Left Ventricular Hypertrophy on the Time-Course of Renal Function in Hypertensive Patients : A Subanalysis of the CASE-J Trial
- Genetic Polymorphisms of L-Type Calcium Channel α1c and α1D Subunit Genes are Associated With Sensitivity to the Antihypertensive Effects of L-Type Dihydropyridine Calcium-Channel Blockers
- PE-213 Diabetes and Chronic Kidney Disease Contribute to Inadequate Blood Pressure Control in Hypertension Treated with Angiotensin Receptor Blocker/Diuretics(PE036,Hypertension, Clinical 2 (H),Poster Session (English),The 73rd Annual Scientific Meeting o
- PJ-687 Utilization of Echocardiography in Stroke Care Unit of Tokushima University Hospital(PJ115,Thromboembolism/Antithrombotic Therapy/Thrombolysis (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-579 Plasma Concentration of Pentraxin 3 is a Useful Marker for Monitoring the Anti-plaque Effect of Telmisartan(PJ097,Cardiovascular Pharmacology (Clinical) (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation So
- PJ-391 Pentraxin 3, a Novel Inflammatory Marker, Predicts Left Ventricular Remodeling in Patients with Acute Myocardial Infarction(PJ066,ACS/AMI (Basic) (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society
- PE-553 Prediction of Cardiac Response to Preload Augmentation by Dual Doppler Echocardiography and Left Arial Volume Auto Tracking System(PE093,Echo/Doppler (Others) (I),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulati
- PE-494 Synthetic Prostacycline Agonist, ONO-1301, Ameliorates Left Ventricular Dysfunction and Cardiac Fibrosis in Cardiomyopathic Hamsters(PE083,Cardiovascular Pharmacology (Basic), Cost-health Care System/DPC/Laws (H),Poster Session (English),The 73rd A
- PE-381 Local Persistent Hypercoagulability after Drug-Eluting Stent Implantation : Sirolimus-Eluting Stent vs. Paclitaxel-Eluting Stent(PE064,Coronary Revascularization, PCI (DES) 6 (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of the
- PE-347 Early Detection of Myocardial Damage in Female Carriers of Duchenne Muscular Dystrophy : the Utility of Cardiac Magnetic Resonance(PE058,Cardiomyopathy/Hypertrophy (Clinical) 1 (M),Poster Session (English),The 73rd Annual Scientific Meeting of The
- PE-342 Angiotensin-II Receptor Blocker Prevents the Deterioration of Left Ventricular Geometry and Diastolic Function in Hypertrophic Cardiomyopathy(PE058,Cardiomyopathy/Hypertrophy (Clinical) 1 (M),Poster Session (English),The 73rd Annual Scientific Meet
- PE-110 Postsystolic Shortening is Superior to Peak Systolic Strain on the Prediction of Ischemia in Normal Wall Motion Segments(PE019,Echo/Doppler (New Technology) (I),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation
- DPJ-022 Elevation of Left Ventricular End-diastolic Pressure Enhances Mismatch between Mitral Inflow and Annular Motion(DPJ04,Heart Failure (Diagnosis) (M),Digital Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation So
- DPE-042 Plasma Aldosterone Concentration is Associated with Cognitive Impairement in Patients with Hypertension(DPE07,Hypertension, Clinical (H),Digital Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- OJ-001 Long-Term Local Inflammatory Response after Coronary Artery Stenting : BMS vs. SES vs. PES(OJ01,Coronary Revascularization, PCI (DES) (IHD),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- OE-366 Bosentan, an Endothelin Receptor Antagonist, Exerts Protective Actions against Systemic Sclerosis-related Peripheral Circulation Insufficiency(OE62,Peripheral Circulation/Vascular Disease (Therapy) (H),Oral Presentation (English),The 73rd Annual Sc
- OE-213 Pitavastatin Exerts LDL Cholesterol Reduction-independent Protective Action for Cardiac and Renal Function in Patients with Dyslipidemia(OE36,Atherosclerosis (Clinical/Treatment) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting
- OE-179 Effect of Ghrelin on Autonomic Activity in Healthy Volunteers(OE31,Cardiovascular Pharmacology (Basic) (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Prevention and regression of hypertension : role of renal microvascular protection
- PE-209 Pitavastatin Excretes eNOS-independent Protective Action against Angiotensin II-induced Atrial Remodeling through Attenuating Rac1-madiated Oxidative Stress(PE035,Cardiovascular Pharmacology (Basic) (H),Poster Session (English),The 73rd Annual Scie
- evidence-based practice guideline for the treatment of chronic kidney disease
- Prevalence of anemia according to stage of chronic kidney disease in a large screening cohort of Japanese
- Heart rate as a risk factor for developing chronic kidney disease : longitudinal analysis of a screened cohort
- Validation of Longitudinal Peak Systolic Strain by Speckle Tracking Echocardiography With Visual Assessment and Myocardial Perfusion SPECT in Patients With Regional Asynergy
- Impact of renal function on cardiovascular events in elderly hypertensive patients treated with efonidipine : Renal Subset Analysis of the Japanese Trial to Assess Optimal Systolic Blood Pressure in Elderly Hypertensive Patients (JATOS)
- Confirmation of ALDH2 as a Major Locus of Drinking Behavior and of Its Variants Regulating Multiple Metabolic Phenotypes in a Japanese Population
- Influence of Coronary Risk Factors on Coronary Events in Japanese High-Risk Hypertensive Patients : Primary and Secondary Prevention of Ischemic Heart Disease in a Subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) Trial
- Japan Renal Biopsy Registry : the first nationwide, web-based, and prospective registry system of renal biopsies in Japan
- T-Type Ca Channel Blockade as a Determinant of Kidney Protection
- How to use marginal structural models in randomized trials to estimate the natural direct and indirect effects of therapies mediated by causal intermediates
- Long-term effects of candesartan and amlodipine on cardiovascular morbidity and mortality in Japanese high-risk hypertensive patients : the Candesartan Antihypertensive Survival Evaluation in Japan Extension Study (CASE-J Ex)
- Combination therapy for hypertension in the elderly : a sub-analysis of the Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) Trial
- Baro-excited neurons in the caudal ventrolateral medulla (CVLM) recorded using the whole-cell patch-clamp technique
- Importance of rostral ventrolateral medulla neurons in determining efferent sympathetic nerve activity and blood pressure
- Optimal Combination of Effective ANtihypertensives (OCEAN) study : a prospective, randomized, open-label, blinded endpoint trial-rationale, design and results of a pilot study in Japan
- Cardiac Magnetic Resonance Imaging and 2-Dimensional Speckle Tracking Echocardiography in Secondary Cardiac Amyloidosis
- Evaluation of genetic loci influencing adult height in the Japanese population
- Hunting for genes for hypertension : the Millennium Genome Project for Hypertension