Takashima Hiroaki | Department Of Cardiology Aichi Medical University
スポンサーリンク
概要
関連著者
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Takashima Hiroaki
Department Of Cardiology Aichi Medical University
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Itoh Takayuki
Department Of Cardiology Aichi Medical University
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Takashima Hiroaki
Department of Cardiology,Aichi Medical University School of Medicine
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WAKITA Yoshinori
Department of Applied Chemistry, Graduate School of Engineering, Nagoya University
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Kuroda Yasuo
Department of Cardiology,Aichi Medical University School of Medicine
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Kuhara Yasushi
Department Of Cardiology Aichi Medical University
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Wakita Yoshinori
Department Of Cardiology Aichi Medical University
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Wakita Yoshinori
Department Of Applied Chemistry Graduate School Of Engineering Nagoya University
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Asai Kenji
Department Of Bioregulation Research Nagoya City University
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KURODA Yasuo
Department of Cardiology, Aichi Medical University
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Wakida Yasushi
Department Of Cardiology Aichi Medical University
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Wakida Yasushi
The 3rd Department Of Internal Medicine Aichi Medical University
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Asai Kenji
Department of Cardiology,Aichi Medical University School of Medicine
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Asai Kenji
Department Of Cardiology Aichi Medical University
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Itoh Takayuki
Department Of Applied Physics Waseda University
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Kuhara Yasushi
Department of Cardiology,Aichi Medical University School of Medicine
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Takagi Kazuaki
Department Of Cardiology Aichi Medical University
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Kohsaka Takashi
Department of Cardiology,Aichi Medical University School of Medicine
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Kohsaka Takashi
Department Of Cardiology Ogaki Municipal Hospital
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Kohsaka Takashi
Department Of Cardiology Aichi Medical University
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Waseda Katsuhisa
Center For Research In Cardiovascular Interventions Stanford University Medical Center
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Ozaki Yukio
Divisoin Of Cardiology Fujita Health University School Of Medicine
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Wakamatsu Yoshitaka
Department Of Cardiology Aichi Medical University
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Ozaki Yukio
Department Of Cardiology Fujita Health University School Of Medicine
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Yasukawa Tatsuya
Yasukawa Clinic
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Ozaki Yukio
Aichi Medical University
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Ozaki Yukio
Division Of Cardiology Fujita Health University Hospital
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Wakamatsu Yoshitaka
2nd Dept.of Internal Med. Nagoya Univ.school Of Med.
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Ito Takayuki
Division Of Cardiology Aichi Medical University School Of Medicine
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Itoh Takayuki
Department Of Cardiology Aichi Medical University School Of Medicine
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Yasukawa Tatsuya
Department of Cardiology, Aichi Medical University
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Kohno Tomohiro
Seki Central Hospital
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Shinjo Hiroyuki
Department Of Cardiology Aichi Medical University
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Shinjoh Hiroyuki
Department of Cardiology, Aichi Medical University
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Kohno Tomohiro
Department of Cardiology, Aichi Medical University
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OZAKI Yukio
Division of Cardiology, Department of Internal Medicine, Fujita Health University, School of Medicin
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Ozaki Yukio
Division Of Cardiology Department Of Internal Medicine Fujita Health University School Of Medicine
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Kurita Akiyoshi
Department Of Cardiology Aichi Medical University
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Mizuno Tomofumi
Department Of Cardiology Aichi Medical University
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Ozaki Yukio
Division Of Acute Coronary Syndrome Aichi Council Of Advanced Emergency Care
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Maeda Kazuyuki
Department Of Applied Chemistry Graduate School Of Engineering Tokyo University Of Agriculture And T
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Maeda Kazuyuki
Department of Cardiology,Aichi Medical University School of Medicine
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Mizuno Tomofumi
Department of Cardiology,Aichi Medical University School of Medicine
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Kurita Akiyoshi
Department of Cardiology,Aichi Medical University School of Medicine
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Maeda Kazuyuki
Department Of Cardiology Aichi Medical University
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Maeda Kazuyuki
Department Of Applied Chemistry Tokyo University Of Agriculture And Technology
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HISHIDA Hitoshi
Division of Cardiology, Department of Internal Medicine, Fujita Health University School of Medicine
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Hishida H
Department Of Cardiology Nagoya Memorial Hospital
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Hishida Hitoshi
Division Of Cardiology Fujita Health University
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Hishida Hitoshi
Division Of Cardiology Department Of Internal Medicine Fujita Health University School Of Medicine
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WASEDA Katsuhisa
Center for Research in Cardiovascular Interventions, Stanford University
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Waseda Katsuhisa
Center For Research In Cardiovascular Interventions Stanford University
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Waseda Katsuhisa
Department of Cardiology, Aichi Medical University
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Ozaki Yukio
Department Of Cardiology Aichi Medical University
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OZAKI Yukio
Department of Clinical and Laboratory Medicine, Faculty of Medicine, University of Yamanashi
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Hishida H
Department Of Cardiology Fujita Health University
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Kakihana Masashi
Department of Cardiology, Aichi Medical University
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Kakihana Masashi
Department Of Cardiology Aichi Medical University
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wakabayashi hirokazu
Department of Cardiology,Aichi Medical University School of Medicine
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Yasukawa Tatsuya
Yasukawa Clinic & Aichi Medical University
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Wakabayashi Hirokazu
Department Of Cardiology Aichi Medical University School Of Medicine
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Wakida Yasushi
Department of Cardiolgy, Aichi Medical University
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Watanabe Atsushi
Department of Cardiology, Aichi Medical University
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Watanabe Atsushi
Department Of Cardiology Aichi Medical University
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Watanabe Atsushi
Department Of Biochemistry And Molecular Biology Nippon Medical School
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Ito Takayuki
Department Of Health Sciences Nagoya University School Of Medicine
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Ozaki Atsuko
Department of Cardiology, Aichi Medical University
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Serruys PW
Thoraxcenter Erasmus University
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Ozaki Atsuko
Department Of Cardiology Aichi Medical University
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Ito Takayuki
Department Of Cardiology Aichi Medical University
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KOSAKA Takashi
Department of Cardiology, Aichi Medical University
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Kosaka Takashi
Department of Cardiology, Aichi Medical University, School of Medicine
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Amano Tetsuya
Department Of Cardiology Chubu-rosai Hospital
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Urade Yoshihiro
Department of Molecular Behavioral Biology, Osaka Bioscience Institute
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Kadota Kazushige
Division of Cardiology, Kurashiki Central Hospital
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SUZUKI Yasushi
Department of Urology, Iwate Medical University
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Suzuki Yasushi
Department Of Cardiology Aichi Medical University
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Miyauchi Katsumi
Department Of Cardiology Juntendo University School Of Medicine
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Harada Ken
Department of Cardiology, Nagoya University Graduate School of Medicine
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AKO Junya
Center for Research in Cardiovascular Interventions, Stanford University
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Iwa Toru
Department of Cardiolgy, Aichi Medical University
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Kato Isao
Department of Cardiolgy, Aichi Medical University
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NAGATA Yoshihisa
Department of Surgery, Aichi Medical University
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AOYAMA Takahiko
Department of Clinical Pharmacokinetics, College of Pharmacy, Nihon University
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KAWAGUCHI Osamu
Department of Radiology, Keio University
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Iwa Toru
Department Of Cardiology Aichi Medical University
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Iwa Toru
Department Of Cardiology Aichi Medical University School Of Medicine
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Iwa Toru
Division Of Cardiology Aichi Medical University School Of Medicine
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Kato Isao
Department Of Cardiology Aichi Medical University
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Kimura Kazuo
Division Of Cardiology Yokohama City University Medical Center
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Ismail Tevfik
Department of Cardiology, Watford General Hospital
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Waseda Katsuhisa
The first two authors contributed equally
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Yasukawa Tatsuya
Cardiology Division, Yasukawa Clinic
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Hirano Jyunko
Department of Mycrobiology and Immunology, Aichi Medical University
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Yoshida Tomoaki
Department of Mycrobiology and Immunology, Aichi Medical University
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Eguchi Yutaka
Intensive Care Unit, Shiga University of Medical Science
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Fukuda Sachiko
Department of Cardiology, Aichi Medical University
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noguchi hiroshi
advanced critical care center, Aichi Medical University
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nakagawa takashi
advanced critical care center, Aichi Medical University
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inoue yasusuke
advanced critical care center, Aichi Medical University
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Kato I
Department Of Cardiology Aichi Medical University
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Nagata Yoshihisa
Department Of Cardiac Surgery Aichi Medical University
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Iwa Toru
Third Department Of Internal Medicine Aichi Medical University
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Ako Junya
Center For Research In Cardiovascular Interventions Stanford University
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Tanabe Kengo
Division Of Cardiology Mitsui Memorial Hospital
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Shinke Toshiro
Division Of Cardiovascular And Respiratory Medicine Department Of Internal Medicine Kobe University
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Hasegawa Takao
Division Of Cardiology Seichokai Fuchu Hospital
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Fukuda Sachiko
Department Of Cardiology Aichi Medical University
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Daida Hiroyuki
Department Of Cardiology
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Aoyama Takahiko
Department Of Cardiac Surgery Aichi Medical University
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Kato Bunichi
Department Of Cardiology Chubu Rosai Hospital
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Nagata Yoshihisa
Second Department Of Surgery Aichi Medical University
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Kunimura Ayako
Department Of Cardiology Chubu Rosai Hospital
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Muramatsu Toshiya
Division Of Cardiology Kawasaki Social Insurance Hospital
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Nakagawa Yoshihisa
Department Of Cardiology Kokura Memorial Hospital
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Morino Yoshihiro
Division Of Cardiology Department Of Internal Medicine Tokai University School Of Medicine
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Yoshida Tomoaki
Department Of Materials Science Faculty Of Engineering Tohoku University
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Ino Yasushi
Department Of Cardiovascular Medicine National Cardivascular Center
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Urade Yoshihiro
Department Of Molecular Behavioral Biology Osaka Bioscience Institute
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Urade Yoshihiro
Department Of Molecular Behavioral Biology Japan Science And Technology Corporation Osaka Bioscience
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Igarashi Keiichi
Division Of Cardiology Hokkaido Central Hospital For Social Insurance
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Kawaguchi Osamu
Department Of Cardiac Surgery Aichi Medical University
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Kubo Takashi
Department Of Anesthesia Akane Foundation Tsuchiya General Hospital : Present Address: Department Of
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Eguchi Yutaka
Intensive Care Unit Shiga University Of Medical Science
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Ismail Tevfik
Department Of Cardiology And Internal Medicine Colchester General Hospital
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Ismail Tevfik
Department Of Cardiology Watford General Hospital
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Hirano Jyunko
Department Of Mycrobiology And Immunology Aichi Medical University
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Inoue Yasusuke
Advanced Critical Care Center Aichi Medical University
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Okura Hiroyuki
Division Of Cardiology Bell Land General Hospital
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Matsuzaki Masunori
Division Of Cardiology Department Of Medicine And Clinical Science Graduate School Of Medicine Yamag
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Kimura Takeshi
Division Of Cardiology Kyoto University Hospital
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Hiro Takafumi
Division Of Cardiology Department Of Internal Medicine Nihon University School Of Medicine
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Ando Hirohiko
Department Of Cardiology Chubu-rosai Hospital
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Uetani Tadayuki
Department Of Cardiology Chubu-rosai Hospital
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Kato Masataka
Department Of Cardiology Chubu-rosai Hospital
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Matsubara Tatsuaki
Department Of Cardiology Nagoya University Graduate School Of Medicine
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Ishii Hideki
Department Of Cardiology Nagoya Graduate School Of Medicine
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Kawaguchi Osamu
Department Of Applied Chemistry Faculty Of Engineering Saitama University
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Yoshida Tomoaki
Department Of Mycrobiology And Immunology Aichi Medical University
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Murohara Toyoaki
Department Of Cardiology Nagoya Graduate School Of Medicine
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Nakagawa Yoshihisa
Division Of Cardiology Tenri Hospital
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Suzuki Yasushi
Department Of Applied Chemistry School Of Engineering Tokai University
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Urade Yoshihiro
Department Of Behavioral Biology Osaka Bioscience Institute
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Fusazaki Tetsuya
Division Of Cardiology Department Of Internal Medicine And Memorial Heart Center Iwate Medical Unive
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Suzuki Akihiro
Department Of Anesthesiology And Critical Care Medicine Asahikawa Medical College
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Yamaguchi Hiroshi
Division Of Cardiology Department Of Internal Medicine Juntendo Universit.y School Of Medicine
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Akasaka Takashi
Department Of Cardiology Kawasaki Medical School
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Kozuma Ken
Division Of Cardiology Department Of Internal Medicine Teikyo University School Of Medicine
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Yamagishi Masakazu
Division Of Cardiology Department Of Internal Medicine Kanazawa University Graduate School Of Medici
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Noguchi Hiroshi
Advanced Critical Care Center Aichi Medical University
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Nakagawa Takashi
Advanced Critical Care Center Aichi Medical University
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Suzuki Yasushi
Department Of Agricultural Chemistry The University Of Tokyo
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Kato Isao
Third Department Of Internal Medicine. Aichi Medical University
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Takashima Hiroaki
Department of Cardiology, Aichi Medical University
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MORIMOTO Takeshi
Center for General Internal Medicine and Emergency Care, Kinki University School of Medicine
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AMANO Tetsuya
Department of Cardiology, Aichi Medical University
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OZAKI Yukio
Department of Cardiology, Fujita Health University
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HIRO Takafumi
Division of Cardiology, Department of Medicine, Nihon University School of Medicine
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Yamagishi Masakazu
Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine
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Kurita Akiyoshi
Department of Cardiology, Aichi Medical University
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Kuhara Yasushi
Department of Cardiology, Aichi Medical University
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Mizuno Tomofumi
Department of Cardiology, Aichi Medical University
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KIMURA Takeshi
Department of Applied Chemistry and Molecular Science, Faculty of Engineering, Iwate University
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YOSHIDA TOMOHIRO
Department of Anatomy and Histology, Kurume University School of Medicine
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Takamisawa Itaru
Division of Cardiology, Sakakibara Memorial Hospital
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Hasegawa Takao
Division of Cardiovascular Medicine, Osaka City University Hospital
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Muramatsu Toshiya
Division of Cardiology, Saiseikai Yokohamashi Tobu Hospital
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HARADA Kazuhiro
Department of Cardiology,Chubu Rosai Hospital
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SHIMBO Yusaku
Department of Cardiology,Chubu Rosai Hospital
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KITAGAWA Katsuhide
Department of Cardiology,Chubu Rosai Hospital
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MUROHARA Toyoaki
Department of Cardiology,Nagoya University Graduate School of Medicine
著作論文
- PJ-331 Influence of Valsartan on the prevention of Atherosclerotic Coronary plaque : Three-dimensional Intracoronary Ultrasound (3D-IVUS) and Quantitative Coronary Angiography (QCA) Study(Hypertension, clinical(08)(H),Poster Session(Japanese),The 72nd Ann
- PJ-135 Comparison between Women and Men in Vessel Dimension, Plaque Burden and Restenosis Assessed by Intracoronary Ultrasound (IVUS) and Quantitative Coronary Angiography (QCA)(Restenosis, basic/clinical-6 (IHD) PJ23,Poster Session (Japanese),The 70th An
- Influence of Hypertension on Lesion Morphology, Vessel Remodeling and Restenosis : An Intracoronary Ultrasound (IVUS) and Quantitative Coronary Angiographic (QCA) Study(Hypertension, Clinical 2 (H), The 69th Annual Scientific Meeting of the Japanese Circu
- Impact of Lipid-Lowering Therapy With Pitavastatin, a New HMG-CoA Reductase Inhibitor, on Regression of Coronary Atherosclerotic Plaque : A 3-Dimensional Intravascular Ultrasound Study
- OJ-135 Impact of Statin on New Cardiovascular Events Following Coronary Intervention and on Coronary Plaque Regression : A Three-Dimensional Intravascular Ultrasound Study(Atherosclerosis, clinical-03, The 71st Annual Scientific Meeting of the Japanese Ci
- Impact of Angiotensin II Receptor Blockers on the Progression and Regression of Coronary Atherosclerosis : An Intravascular Ultrasound Study
- PJ-145 Impact of Diabetes on 6-month Angiographic and 3-year Clinical Outcomes after Intracoronary Ultrasound (IVUS) Guided Stent Implantation(Diabetes/Obesity/Metabolic syndrome-10 (H) PJ25,Poster Session (Japanese),The 70th Anniversary Annual Scientific
- OJ-371 Influence of Lipid-lowering Therapy with Strong-statin on Prevention of Progression of Coronary Plaque in the LMT; A 3D-IVUS Study(Atherosclerosis, clinical-5 (H) OJ62,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of t
- OJ-130 Comparison of Three-Year Clinical and Angiographic Outcome among Coronary Stent, Bypass Graft (CABG) and Medication (MED) for Left Anterior Descending Artery (LAD) Lesions(Acute coronary syndrome, basic/clinical-2 (IHD) OJ22,Oral Presentation (Japa
- Relation of Left Main Stem (LMT) Plaque Burden and the Stages of Coronary Artery Disease ; An Intracoronary Ultrasound (IVUS) Study (Angina Pectoris, Basic/Clinical 4 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Influence of Low-Dose-Statin on the Progression and Regression of Left Main Coronary Artery Atherosclerosis Estimated by Three-Dimensional Intracoronary Ultrasound (3D-IVUS)(Intravascular Endoscopy/Intravascular Ultrasound 1 (I), The 69th Annual Scientifi
- Impact of Low-Dose Statin on 6-month Angiographic Restenosis and 3-year Clinical Outcome Following Intracoronary Ultrasound (IVUS) Guided Stenting(Lipid Disorders 4 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Influence of Angiotensin Receptor Blocker (ARB) and Statin on the Prevention of Coronary Atherosclerosis Progression : A 3D Intravascular Ultrasound(IVUS) Study(Atherosclerosis, Clinical 15 (IHD), The 69th Annual Scientific Meeting of the Japanese Circula
- PJ-565 "Stent Edge Effect" and In-Stent Restenosis (ISR) in Open Cell and Closed Cell Stents Assessed by 3D Intracoronary Ultrasound (3D-IVUS)(Restenosis after Angioplasty, Basic/Clinical 7 (IHD) : PJ95)(Poster Session (Japanese))
- PJ-561 Impact of Calcium Deposit on the Mechanism of Late Restenosis After Stenting and Balloon Angioplasty (POBA)(Restenosis after Angioplasty, Basic/Clinical 6 (IHD) : PJ94)(Poster Session (Japanese))
- PJ-532 Influence of Current, Previous and Non-Smoking on Coronary Atherosclerosis and Restenosis Assessed by Intracoronary Ultrasound (IVUS)(Smoking 2 (H) : PJ89)(Poster Session (Japanese))
- PJ-330 Impact of Vascular Remodelling Mode on the Mechanism of Acute Gain and Late Restenosis Following Balloon Angioplasty (POBA) and Stent(Intravascular Endoscopy/Intravascular Ultrasound 3 (I) : PJ55)(Poster Session (Japanese))
- PJ-325 Impact of Statin on the Prevention of Progression of Coronary Atherosclerosis in Left Main Stem (LMT) Assessed by Serial Intracoronary Ultrasound (ICUS)(Intravascular Endoscopy/Intravascular Ultrasound 2 (I) : PJ54)(Poster Session (Japanese))
- OJ-479 Role of Serum Level of Lipocalin-Type Prostaglandin-D Synthase (L-PGDS) on Coronary Atherosclerosis assessed by Quantitative Coronary Angiography (QCA) and Genetic Analysis (SNP analysis)(Angina Pectoris, Clinical 3 (IHD) : OJ58)(Oral Presentation
- OJ-381 Role of Statin in the Prevention of In-stent Restenosis : a Quantitative Coronary Angiography (QCA) Study(Restenosis after Angioplasty, Basic/Clinical 3 (IHD) : OJ46)(Oral Presentation (Japanese))
- PJ-720 Effects of Angiotensin Receptor Blocker (Valsartan) on Prevention of Newly Cardiac Events in Patients with Coronary Artery Disease(PJ121,Hypertension, Clinical 2 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circu
- PE-391 Impact of Abnormal Glucose Tolerance on Progression of Coronary Atherosclerosis : A Serial Volumetric Intravascular Ultrasound (IVUS) Study(PE066,Diabetes 2 (H),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation
- PE-370 Unfavorable Effects of Cigarette Smoking on Coronary Atherosclerosis : A Serial Volumetric Intravascular Ultrasound (IVUS) Study(PE062,Atherosclerosis (Clinical/Treatment) (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of The Jap
- OE-211 Impact of Optimal Lipid Management on Prevention of Coronary Artery Plaque Progression : A Serial Volumetric IVUS Study(OE36,Atherosclerosis (Clinical/Treatment) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese C
- OE-098 Mechanism of Late Incomplete Stent Apposition of Sirolimus-Eluting Stent (SES) in Acute Coronary Syndrome (ACS) is Different from in non-ACS(OE17,Coronary Revascularization, PCI (Restenosis/Others/DES) (IHD),Oral Presentation (English),The 73rd Ann
- PJ-825 The Relationship between Plaque Prolapse Phenomenon and Late Incomplete Stent Apposition in Acute Coronary Syndrome Patients Implanted Sirolimus Eluting Stents(Coronary revascularization, PCI(27)(IHD),Poster Session(Japanese),The 72nd Annual Scient
- PJ-655 The Outcomes of Cobalt-alloy Driver Stent Implantation for the Large Vessels, Comparison with Sirolimus-eluting Stent : Quantitative Coronary Angiography (QCA) study(Coronary revascularization, PCI(24)(IHD),Poster Session(Japanese),The 72nd Annual
- PE-505 Comparison of Two-Year Clinical and Angiographic Outcome among Drug-Eluting Stent, Bare-Metal Stent and Bypass Graft (CABG) in Dialysis Patients(Coronary revascularization, PCI(15)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of
- OE-047 Relationship Between Improvement in Serum ApoB/ApoA-1 Ratio and the Progression of Coronary Artery Plaque with Pitavastatin : A 3D-IVUS Study(Atherosclerosis, clinical(01)(IHD),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Ja
- PJ-738 The Efficacy of Drug-Eluting Stent for the Treatment of Small Coronary Artery Disease, Comparison with Bare-Metal Stent and Bypass Surgery(Coronary revascularization, PCI-19, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-737 The Efficacy of Drug-Eluting Stent for the Treatment of Left Anterior Descending lesion, Comparison with Bare-Metal Stent and Bypass Surgery(Coronary revascularization, PCI-19, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-609 Impact of Statin on Long-term Cardiovascular Events in Patients with Impaired Glucose Tolerance and Diabetes(Diabetes/Obesity/Metabolic syndrome-09, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OE-013 Survivors from Arrest by Automated External Defibrillators in EXPO 2005(Emergency care-1 (H) OE3,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- PE-120 Early- and Long-term Outcomes of Plaque Prolapse Phenomenon in Acute Coronary Syndrome (ACS) Patients(Acute coronary syndrome, basic/clinical(03)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-365 Comparison of Percutaneous Coronary Intervention (PCI), Medical Therapy (MED) and coronary bypass grafts (CABG) on Small Vessel Disease : A Matched Comparison by Quantitative Coronary Angiography (QCA)(Coronary Revascularization, PTCA/Stent/DCA/Rot
- OJ-363 Statin Therapy Following Intracoronary Ultrasound (ICUS) Guided Coronary Stent Implantation and Three-year Event Free Survival(Coronary Revascularization, PTCA/Stent/DCA/Rotablator/New Device 10 (IHD) : OJ44)(Oral Presentation (Japanese))
- Clustering of Metabolic Syndrome Components Attenuates Coronary Plaque Regression During Intensive Statin Therapy in Patients With Acute Coronary Syndrome : The JAPAN-ACS Subanalysis Study
- Vascular Response to Drug-Eluting Stent With Biodegradable vs. Durable Polymer:– Optical Coherence Tomography Substudy of the NEXT –
- Prognostic impact of concurrence of metabolic syndrome and chronic kidney disease in patients undergoing coronary intervention:Involvement of coronary plaque composition