Synthesis and Oral Absorption of Hetacillin and Hetamoxicillin Labile Esters(Medicinal Chemistry,Chemical)

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概要

• 論文の詳細を見る

• Nine esters of hetacillin or hetamoxicillin were synthesized as ampicillin and amoxicillin derivatives with the aim of obtaining improved plasma levels after oral administration. Out of these esters, which are devoid of apparent toxic effects, the benzyloxymethyl ester of hetacillin(FI-5204) gave the best result and was chosen for subsequent studies.

• 公益社団法人日本薬学会の論文
• 1987-06-25

著者

• Gubert Santiago

  Centro De Investigation Grupo Ferrer

• PALACIN CELIA

  Centro de Investigation Grupo Ferrer

• SACRISTAN AURELIO

  Centro de Investigation Grupo Ferrer

• ORTIZ JOSE

  Centro de Investigation Grupo Ferrer

関連論文

• Synthesis and Oral Absorption of Hetacillin and Hetamoxicillin Labile Esters(Medicinal Chemistry,Chemical)

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