リフィーディング症候群 (特集メンタルヘルスと栄養)

概要

論文の詳細を見る
Refeeding syndrome is a potentially fatal medical condition that may affect malnourished patientsin response to an inappropriately rapid overfeeding. This commonly occurs following the institutionof nutritional support, especially parenteral or enteral nutrition. The most characteristic pathophysiologyof refeeding syndrome relates to the rapid consumption of phosphate after glucose intake andsubsequent hypophosphatemia. Refeeding syndrome can manifest as either metabolic changes（hypokalaemia, hypophosphataemia, vitamin B１deficiency, and altered glucose metabolism）orphysiological changes（cardiac arrhythmias, unconsciousness, seizures, cardiac or respiratory depression）and potentially death. Preventing refeeding syndrome is the primary goal when initiatingnutrition support in severely malnourished patients. Clinicians should be aware of refeeding syndromewhen they treat malnourished patients, and most importantly take appropriate steps（carefulmonitoring）to prevent refeeding syndrome.
2012-04-25