Improvement of the Detection Accuracy and Detection Limit of a Filter-less Fluorescence Detector
スポンサーリンク
概要
- 論文の詳細を見る
Filter-less fluorescence detectors (FFDs) do not require any optical filters for multicolor fluorescence detection. Therefore, a small and low-cost fluorescence detector is realizable, and applications to pathological examination and drug development are expected. In order to apply such devices to biochemical and medical diagnosis, it is important to detect weak fluorescence with high accuracy. However, in some situations, the fluorescence intensity may be less than 10^{-5} of the excitation light intensity. In this study, we experimentally demonstrate an FFD with improved detection accuracy and detection limit. By this approach, the detectable fluorescence intensity decreased to the dark-current level.
- 2013-07-25
著者
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Yamasaki Keita
Integrated Circuit and Sensor System Group, Toyohashi University of Technology, Toyohashi, Aichi 441-8580, Japan
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Nakazawa Hirokazu
Integrated Circuit and Sensor System Group, Toyohashi University of Technology, Toyohashi, Aichi 441-8580, Japan
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Toyofuku Takuya
Integrated Circuit and Sensor System Group, Toyohashi University of Technology, Toyohashi, Aichi 441-8580, Japan
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Akita Ippei
Integrated Circuit and Sensor System Group, Toyohashi University of Technology, Toyohashi, Aichi 441-8580, Japan
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Ishida Makoto
Integrated Circuit and Sensor System Group, Toyohashi University of Technology, Toyohashi, Aichi 441-8580, Japan
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Sawada Kazuaki
Integrated Circuit and Sensor System Group, Toyohashi University of Technology, Toyohashi, Aichi 441-8580, Japan