Nanopore Protein Biosensor Using Diffusive Flow
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概要
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A nanopore protein biosensor using a copolymer and diffusive flow of the test sample was developed. The copolymer coated within the nanopore can capture the antibody, which then captures the antigen. Diffusive flow of a test sample can be obtained using a concentration gradient between the nanopore and the micropore sides. No applied voltage was used to create the electrokinetic flow of the test liquid. The present nanopore protein biosensor showed high sensitivity and detected antigen quantities as low as 0.15 nM (4 pg/mL).
- 2011-12-25
著者
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Kim Tae-hyoung
School Of Mechanical Engineering Chung-ang University
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CHIARI Marcella
Istituto di Chimica del Riconoscimento Molecolare (ICRM)
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Kim Tae-Hyoung
School of Mechanical Engineering, Chung-Ang University, Seoul 156-756, Korea
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Thornton Trevor
Electrical Engineering and Center for Solid State Electronics Research, Arizona State University, Tempe, AZ 85287, U.S.A.
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Jung Jung-Yeul
Marine Safety and Pollution Response Research Department, Maritime and Ocean Engineering Research Institute, KORDI, Daejon 305-343, Korea
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Chiari Marcella
Istituto di Chimica del Riconoscimento Molecolare, CNR, Milano, Italy
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- Nanopore Protein Biosensor Using Diffusive Flow