Measurement of Glucose Level Exploiting a Relative Optical Absorption at Discrete Probe Wavelengths

概要

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A practical and viable scheme for measuring the concentration of a glucose solution was proposed and verified based on the relative optical absorbance at discrete probe wavelengths instead of the continuous broad band absorption spectra. The relative absorbance at each of the probe wavelengths was obtained with respect to the absorbance at a reference wavelength. The single reference wavelength (1310 nm) and a group of four different probe wavelengths (1064, 1550, 1685, 1798 nm) were selected to exhibit the glucose absorbance with opposite signs, thereby enhancing the accuracy of the prediction. The glucose level was decently estimated by taking the average of all of the individual prediction values available from each of the probe wavelengths, with the standard error of prediction of ${\sim}28$ mg/dL. And the influence of the ambient temperature upon the prediction of the glucose concentration was examined to compensate for the error induced by the variation in it. The effect of both the amplification of the sensor signal and the optical path length upon the performance of the proposed scheme was briefly addressed as well.
2009-07-25