Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
スポンサーリンク
概要
- 論文の詳細を見る
The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) project is a joint initiative of the societies of toxicological pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP) and North America (STP). Its aim is to develop an internationally-accepted nomenclature for proliferative and non-proliferative lesions in laboratory rodents. A widely accepted international harmonization of nomenclature in laboratory animals will decrease confusion among regulatory and scientific research organizations in different countries and will provide a common language to increase and enrich international exchanges of information among toxicologists and pathologists. The purpose of this publication is to provide a standardized nomenclature for classifying microscopical lesions observed in the integument of laboratory rats and mice. Example colour images are provided for most lesions. The standardized nomenclature presented in this document and additional colour images are also available electronically at http://www.goreni.org. The nomenclature presented herein is based on histopathology databases from government, academia, and industrial laboratories throughout the world, and covers lesions that develop spontaneously as well as those induced by exposure to various test materials. (DOI: 10.1293/tox.26.27S; J Toxicol Pathol 2013; 26: 27S–57S)
- 日本毒性病理学会の論文
著者
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Bradley Alys
Charles River, Tranent, Edinburgh, UK
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Mecklenburg Lars
mecklenburg-consulting, Hamburg, Germany
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Kusewitt Donna
UT MD Anderson Cancer Center, Smithville, Texas, USA
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Kolly Carine
Novartis Pharma AG, Basel, Switzerland
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Treumann Silke
BASF SE, Ludwigshafen, Germany
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Adams E.
Experimental Pathology Laboratories, Inc, Research Triangle Park, North Carolina, USA
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Diegel Kelly
Hoffmann La-Roche Nonclinical Safety, Nutley, New Jersey, USA
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Yamate Jyoji
Osaka Prefecture University, Osaka, Japan
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Kaufmann Wolfgang
Merck Serono Research & Development, Darmstadt, Germany
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Müller Susanne
Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany
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Danilenko Dimitry
Genentech, South San Francisco, California, USA