Comparison between Two Separate Injections and a Single Injection of Double-dose Contrast Medium for Contrast-enhanced MR Imaging of Metastatic Brain Tumors
スポンサーリンク
概要
- 論文の詳細を見る
Purpose: As stereotactic radiotherapy (SRT) becomes widespread, precise information including number, location, and margin of lesions is required when magnetic resonance (MR) imaging of brain metastasis is performed. We compare methods using 2 separate injections and a single injection for the administration of a double dose of contrast medium for contrastenhanced MR imaging.<br/>Materials and Methods: We divided 40 patients with brain metastasis into 2 groups of 20 patients. Group A received 2 separate injections (0.2 + 0.2 mL/kg) of contrast medium (gadoteridol); Group B received a single injection of the same total dose (0.4 mL/kg). Group A underwent spin echo (SE) T1-weighted imaging (T1WI) and magnetization prepared rapid acquisition with gradient echo sequence (MPRAGE) after each injection, and Group B underwent the same MR studies at the same timing as Group A. We evaluated the number, signal-to-noise ratio (SNR), diameter, margin delineation, and volume of lesions and compared them between early and delayed studies by the 2 methods.<br/>Results: The number of detected lesions was largest in delayed studies of MPRAGE in both groups. The SNR of the lesions was statistically lower in early studies of Group A than other studies. Delayed studies of Group B showed statistically better margin delineation than other studies on both SE-T1WI and MPRAGE studies. Diameter and enhanced volume were statistically significantly larger on delayed phase than early phase in both groups.<br/>Conclusion: Use of a single injection of double-dose contrast medium and longer delay time may improve margin delineation of lesions for the study of brain metastasis. Enhanced volume was larger on delayed phase, and it may influence selection of therapeutic strategy.
- 日本磁気共鳴医学会の論文
日本磁気共鳴医学会 | 論文
- Development of a Hyperpolarized ^Xe System on 3T for the Rat Lungs
- Diagnosis of Unruptured Intracranial Aneurysms : 3T MR Angiography versus 64-channel Multi-detector Row CT Angiography
- Sensitivity of an Eight-element Phased Array Coil in 3 Tesla MR Imaging : A Basic Analysis
- Superparamagnetic Iron Oxide (SPIO) MRI Contrast Agent for Bone Marrow Imaging : Differentiating Bone Metastasis and Osteomyelitis
- Correlation between High Field MR Images and Histopathological Findings of Rat Transplanted Cancer Immediately after Partial Microwave Coagulation