Hypopituitarism Possibly due to Lymphocytic Hypophysitis in a Patient with Type 1 Diabetes

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概要

• 論文の詳細を見る

• Hypopituitarism often develops insidiously, and undiagnosed hypopituitarism can influence the glycemic profile of patients with type 1 diabetes. We herein report the case of a 49-year-old man with type 1 diabetes and Hashimoto's thyroiditis who experienced an unexplained improvement in his glycemic level and recurrent severe hypoglycemia, despite a reduction in the dose of insulin. Based on the patient's endocrinological findings, he was diagnosed with hypopituitarism possibly due to lymphocytic hypophysitis, as supported by positive results for human leukocyte antigen A24 and Cw3. Following the administration of hydrocortisone replacement therapy, his insulin requirement increased to a premorbid level, and the severe hypoglycemia resolved.

• 一般社団法人 日本内科学会の論文

著者

• Yamazaki Hiroyuki

  Department of Cardiology, Ashikaga Red Cross Hospital, Japan

• Matoba Keiichiro

  Department of Internal Medicine, Kawaguchi Municipal Medical Center, Japan

• Mitsuishi Sumie

  Department of Internal Medicine, Kawaguchi Municipal Medical Center, Japan

• Hayashida Satoshi

  Department of Internal Medicine, Kawaguchi Municipal Medical Center, Japan

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• Hypopituitarism Possibly due to Lymphocytic Hypophysitis in a Patient with Type 1 Diabetes

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