Effects of Nano-hydroxyapatite Content on Bone Formation in Nano-hydroxyapatite-collagen Composite Membrane with BMP-2 Application
スポンサーリンク
概要
- 論文の詳細を見る
The effects of calcium and phosphate contents on bone formation activity by BMP-2 with nano-hydroxyapatite-collagen composites (nHACs) were evaluated. Nanosize crystallites with different concentrations of hydroxyapatite were successfully fabricated by changing the mixing ratio of calcium solution and phosphate-containing neutralization buffer. Composites were implanted into the subcutaneous tissue in the Wistar male rats with BMP-2 for 2 and 4 weeks. nHAC was degraded and inflammation in the surrounding area decreased with time.Ectopic bone formation was observed around nHACs with higher contents of nano-hydroxyapatite in BMP-2 application at 2 weeks, but was not observed with lower contents at 4 weeks. These results suggest that nHAC with a higher content of nano-hydroxyapatite is suitable as a carrier for BMP-2.
- ナノ・バイオメディカル学会の論文
ナノ・バイオメディカル学会 | 論文
- Effects of Nano-hydroxyapatite Content on Bone Formation in Nano-hydroxyapatite-collagen Composite Membrane with BMP-2 Application
- Effect of Crosslinking Agent in Nanohydroxyapatite-collagen Composite on Ectopic Bone Formation with BMP-2 Application
- An Evaluation of Fluorescent Orthodontic Adhesives Containing Eu-doped ZnO at Room Temperature
- Introduction of Rare-Earth-Element- Containing ZnO Nanoparticles into Orthodontic Adhesives
- Evaluation of Protein Adsorption to Carbon Nanotubes having Different Property, and Identification of Adsorbed Proteins