副鼻腔破壊型真菌症の2症例
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概要
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Fungal rhinosinusitis is classified into noninvasive rhinosinusitis including fungus balls, allergic fungal rhinosinusitis and invasive rhinosinusitis. We report two cases of fulminate fungal rhinosinusitis complicated by orbital and intracranial spread necessitating surgical debridement and medication. Those patients were successfully managed by combination with antifungal therapy and surgical debridement. Those with paranasal invasive mycosis were analyzed literally. Mortality remains unacceptably high, particularly in the subgroup with neurological symptoms, but surgery and effective drugs with different mechanisms of action improved results, over use of a single agent, needs in vitro, in vivo, and clinical validations. Early diagnosis and treatment are important in preventing unfavorable outcomes from such infection.
- 日本鼻科学会の論文
日本鼻科学会 | 論文
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